Wilhelm Filehne (12 February 1844, in Posen – 29 April 1927, in Bensheim) was a German pharmacologist, who specialized in research of antipyretic drugs.[1]

Wilhelm Filehne

He studied medicine at the universities of Heidelberg and Berlin, where his instructors included Emil du Bois-Reymond and Friedrich Theodor von Frerichs. In 1866 he received his doctorate, and afterwards, he worked as assistant under Rudolf Virchow in Berlin. After participation in the Franco-Prussian War, he returned to Berlin as an assistant to Ludwig Traube.[2] In 1874 he relocated to the University of Erlangen, where he worked as an assistant under Wilhelm Olivier Leube at the medical polyclinic.[3]

In 1876 he became an associate professor of pharmacology at Erlangen, and ten years later, was appointed a full professor of the same subject at the University of Breslau.[3] In 1911 he was succeeded at Breslau by Julius Pohl.[4]

In addition to work in the field of pharmacology, he made contributions in his research of optical illusions, being known for his experimentation with a phenomenon known as a Zöllner illusion.[5] The so-called "Filehne illusion" is the illusory motion of a stationary background when smooth pursuit eye movements are made across the stationary background.[6][7]

Selected works

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  • Ueber die einwirkung des morphins auf die athmung, 1879 – On the effect of morphine on respiration.
  • Ueber das Antipyrin, ein neues Antipyreticum, 1884 – On antipyrine, a new antipyretic.[8]
  • Lehrbuch der Arzneimittellehre und Arzneiverordnungslehre, 1887 – Textbook of pharmacology.[9]
  • Ueber das Pyramidon, ein Antipyrinderivat, 1896 – On Pyramidon, an antipyrine derivative.[10]

References

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  1. ^ The Search for Anti-Inflammatory Drugs: Case Histories from Concept to Clinic edited by Vincent J. Merluzzi, Julian Adams
  2. ^ Filehne, Wilhelm at Neue Deutsche Biographie
  3. ^ a b Filehne, Wilhelm Biographisches Lexikon hervorragender Ärzte
  4. ^ Pohl, Julius Heinrich In: Neue Deutsche Biographie (NDB). Band 20, Duncker & Humblot, Berlin 2001, ISBN 3-428-00201-6, S. 583.
  5. ^ Seeing Motion: A History of Visual Perception in Art and Science by Romana Karla Schuler
  6. ^ Haarmeier, Thomas; Thier, Peter (1996). "Modification of the filehne illusion by conditioning visual stimuli". Vision Research. 36 (5): 741–750. doi:10.1016/0042-6989(95)00154-9. PMID 8762303.
  7. ^ Dicke, Peter W.; Chakraborty, Subhojit; Thier, Peter (2008). "Neuronal correlates of perceptual stability during eye movements". European Journal of Neuroscience. 27 (4): 991–1002. doi:10.1111/j.1460-9568.2008.06054.x. PMID 18333969. S2CID 44527643.
  8. ^ Ueber das Antipyrin, ein neues Antipyreticum ZVAB.com
  9. ^ HathiTrust Digital Library (published works)
  10. ^ Ueber das Pyramidon, ein Antipyrinderivat ZVAB.com