William Clifton may refer to:
- Bill Clifton (born 1931), American musician
- Sir William Clifton, 3rd Baronet (1653–1686)
- William Clifton (Australian politician), Members of the Western Australian Legislative Council, 1832–1870
- William Clifton (Canadian politician), in Toronto municipal election, 1946 and 1947
- William Clifton (architect), architect of the IOOF Temple Building
- William Clifton (footballer) (1891–1953), English footballer, played for Leyland, Preston North End and Rochdale
- William de Clifton (fl. 1302-1305), MP for Lancashire
See also
edit- William Cliffton, Philadelphian poet and pamphleteer
- Clifton (surname)