William of Hesse may refer to:
- William I, Landgrave of Hesse (1466–1515), German nobility
- William II, Landgrave of Hesse (1469–1509), German nobility
- William IV, Landgrave of Hesse-Kassel (1532-1592), German nobility
- William I, Elector of Hesse (1743-1821), German nobility
- Prince William of Hesse, or Landgrave William of Hesse-Kassel (1787-1867), German nobility
This disambiguation page lists articles about people with the same name.
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