In molecular biology, XhoI is a type II restriction enzyme EC that recognise the double-stranded DNA sequence CTCGAG and cleaves after C-1.[1] Type II restriction endonucleases (EC) are components of prokaryotic DNA restriction-modification mechanisms that protect the organism against invading foreign DNA. These site-specific deoxyribonucleases catalyse the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
XhoI | |||||||||
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Identifiers | |||||||||
Symbol | XhoI | ||||||||
Pfam | PF04555 | ||||||||
InterPro | IPR007636 | ||||||||
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References
edit- ^ Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF, Gingeras TR (December 1985). "Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products". Nucleic Acids Res. 13 (23): 8441–61. doi:10.1093/nar/13.23.8441. PMC 322144. PMID 3001639.