Xi River virus (XRV) is a putative novel bat virus in the genus Orthoreovirus isolated from fruit bats in Guangdong Province in southern China. It is the first bat reovirus isolated in China.[1][2]
| Xi River virus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Duplornaviricota |
| Class: | Resentoviricetes |
| Order: | Reovirales |
| Family: | Sedoreoviridae |
| Genus: | Orthoreovirus |
| Species: | |
| Virus: | Xi River virus
|
Virology
editGenome
editOnly a partial sequence of XRV was isolated from the fruit bat, but based on its open reading frame it was identified as a reovirus.[1] XRV has the same morphology and high sequence identity as Nelson Bay virus (NBV), and a 10-segmented double-stranded RNA genome, as well as high sequence identity to NBV members.[3][4]
Reoviruses are non-enveloped, double-stranded RNA viruses. They have an icosahedral capsid (T-13) composed of an outer and inner protein shell. The genome contains 10–12 segments grouped into three categories by size: L (large), M (medium) and S (small). Segments range from ~ 3.9 kbp – 1kbp and each segment encodes 1–3 proteins. Reoviridae proteins are denoted by the Greek character corresponding to the segment it was translated from (the L segment encodes for λ proteins, the M segment encodes for μ proteins and the S segment encodes for σ proteins).[3][4]
See also
editReferences
edit- ^ a b Du, L; Lu, Z; Fan, Y; Meng, K; Jiang, Y; Zhu, Y; Wang, S; Gu, W; Zou, X; Tu, C (Aug 2010). "Xi River virus, a new bat reovirus isolated in southern China". Arch Virol. 155 (8): 1295–9. doi:10.1007/s00705-010-0690-4. PMC 7087202. PMID 20495835.
- ^ Jiang, Yu; Wang, Lili; Lu, Zongji; Xuan, Hua; Han, Xiaohu; Xia, Xianzhu; Zhao, Fuguang; Tu, Changchun (2010). "Seroprevalence of Rabies Virus Antibodies in Bats from Southern China". Vector-Borne and Zoonotic Diseases. 10 (2): 177–181. doi:10.1089/vbz.2008.0212. PMID 19492948.
- ^ a b MicrobiologyBytes Archived 2015-05-21 at the Wayback Machine – Reoviruses
External links
edit- "Translation and Open Reading Frames".
- NCBI ORF finder – A web based interactive tool for predicting and analysing ORFs from nucleotide sequences.