YBX2

Y-box-binding protein 2 is a protein that in humans is encoded by the YBX2 gene.

YBX2
Identifiers
Aliases	YBX2, CONTRIN, CSDA3, DBPC, MSY2, Y-box binding protein 2
External IDs	OMIM: 611447; MGI: 1096372; HomoloGene: 22942; GeneCards: YBX2; OMA:YBX2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.1 Start 7,288,263 bp End 7,294,639 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B3 Start 69,935,796 bp End 69,941,605 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis mucosa of transverse colon duodenum gonad medulla oblongata testicle rectum skeletal muscle tissue muscle of thigh Top expressed in seminiferous tubule spermatid spermatocyte zygote primary oocyte secondary oocyte muscle of thigh neural layer of retina interventricular septum genital tubercle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding RNA binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm nucleus fibrillar center Biological process regulation of transcription, DNA-templated translational attenuation transcription by RNA polymerase II spermatogenesis oocyte development regulation of transcription by RNA polymerase II positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51087 53422 Ensembl ENSG00000006047 ENSG00000288504 ENSMUSG00000018554 UniProt Q9Y2T7 Q9Z2C8 RefSeq (mRNA) NM_015982 NM_016875 NM_001347634 RefSeq (protein) NP_057066 n/a Location (UCSC) Chr 17: 7.29 – 7.29 Mb Chr 11: 69.94 – 69.94 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• RNA polymerase II
• Transcription (biology)
• Translation (biology)

Further reading

• Hammoud S, Emery BR, Dunn D, et al. (2009). "Sequence alterations in the YBX2 gene are associated with male factor infertility". Fertil. Steril. 91 (4): 1090–5. doi:10.1016/j.fertnstert.2008.01.009. PMID 18339382.
• Yoshida T, Izumi H, Uchiumi T, et al. (2006). "Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines". Biochim. Biophys. Acta. 1759 (1–2): 80–8. doi:10.1016/j.bbaexp.2006.02.005. PMID 16624424.
• Kohno Y, Matsuki Y, Tanimoto A, et al. (2006). "Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen". Br. J. Cancer. 94 (5): 710–6. doi:10.1038/sj.bjc.6602987. PMC 2361212. PMID 16479255.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.