In molecular biology, the YEATS domain is a protein domain found in a variety of proteins from eukaryotic organisms.[1] YEATS domain proteins are found in a variety of chromatin modification molecular complexes. Structurally the domain has an immunoglobulin like fold.[2] The YEATS domain has shown to bind to acetyllysine protein modifications.[3] In addition to lysine acetylation, the YEATS domain has shown to be a reader domain for various lysine acylations, with highest affinity for lysine crotonylation.[4][5]
^Schulze JM, Wang AY, Kobor MS (2009). "YEATS domain proteins: a diverse family with many links to chromatin modification and transcription". Biochem. Cell Biol. 87 (1): 65–75. doi:10.1139/O08-111. PMID19234524.