Yup is a slang word for yes, see Yes and no. Yup may also refer to:
- YUP (band), a Finnish rock band
- "Yup" (song), a 2015 song by Easton Corbin
- Yukpa language (ISO 639:yup), spoken in Venezuela and Colombia
- An abbreviation for Yellowdog Updater
- Yale University Press
- Young Urban Professional (see Yuppie)