ZNF219

Zinc finger protein 219 is a protein that in humans is encoded by the ZNF219 gene.

ZNF219
Identifiers
Aliases	ZNF219, ZFP219, zinc finger protein 219
External IDs	OMIM: 605036; MGI: 1917140; HomoloGene: 9504; GeneCards: ZNF219; OMA:ZNF219 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 21,090,077 bp End 21,104,722 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C2 Start 52,243,534 bp End 52,258,190 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal gland right adrenal cortex left adrenal cortex muscle layer of sigmoid colon right hemisphere of cerebellum apex of heart mucosa of transverse colon skin of leg gastric mucosa skin of abdomen Top expressed in ventricular zone otic vesicle saccule cerebellar cortex lip thymus neural layer of retina otic placode ascending aorta aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific histamine receptor activity protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component integral component of membrane nucleus Biological process multicellular organism development G protein-coupled receptor signaling pathway regulation of neurotransmitter levels negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated signal transduction positive regulation of chondrocyte differentiation positive regulation of transcription by RNA polymerase II limb bud formation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51222 69890 Ensembl ENSG00000165804 ENSMUSG00000049295 UniProt Q9P2Y4 Q6IQX8 RefSeq (mRNA) NM_001101672 NM_001102454 NM_016423 NM_001253694 NM_001253695 NM_001253696 NM_027248 RefSeq (protein) NP_001095142 NP_001095924 NP_057507 NP_001240623 NP_001240624 NP_001240625 NP_081524 Location (UCSC) Chr 14: 21.09 – 21.1 Mb Chr 14: 52.24 – 52.26 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Paces-Fessy M, Boucher D, Petit E, et al. (2004). "The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins". Biochem. J. 378 (Pt 2): 353–62. doi:10.1042/BJ20030786. PMC 1223961. PMID 14611647.
• Sakai T, Hino K, Wada S, Maeda H (2004). "Identification of the DNA binding specificity of the human ZNF219 protein and its function as a transcriptional repressor". DNA Res. 10 (4): 155–65. doi:10.1093/dnares/10.4.155. PMID 14621294.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

• ZNF219+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.