ZNF24

Zinc finger protein 24 is a protein that in humans is encoded by the ZNF24 gene.

ZNF24
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1X6E, 3LHR
Identifiers
Aliases	ZNF24, KOX17, RSG-A, ZNF191, ZSCAN3, Zfp191, zinc finger protein 24
External IDs	OMIM: 194534; MGI: 1929704; HomoloGene: 5068; GeneCards: ZNF24; OMA:ZNF24 - orthologs
Gene location (Human) Chr. Chromosome 18 (human) Band 18q12.2 Start 35,332,227 bp End 35,345,482 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 A2 Start 24,142,759 bp End 24,153,867 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus corpus callosum inferior ganglion of vagus nerve olfactory bulb pylorus nipple cardia optic nerve subthalamic nucleus buccal mucosa cell Top expressed in medial ganglionic eminence saccule otic placode ventricular zone triceps brachii muscle stria vascularis vastus lateralis muscle pituitary gland otic vesicle cumulus cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity DNA-binding transcription activator activity, RNA polymerase II-specific sequence-specific DNA binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process myelination negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7572 59057 Ensembl ENSG00000172466 ENSMUSG00000051469 UniProt P17028 Q91VN1 RefSeq (mRNA) NM_001308123 NM_006965 NM_001375815 NM_021559 NM_001357447 NM_001357448 RefSeq (protein) NP_001295052 NP_008896 NP_001362744 NP_067534 NP_001344376 NP_001344377 Location (UCSC) Chr 18: 35.33 – 35.35 Mb Chr 18: 24.14 – 24.15 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Rousseau-Merck MF, Huebner K, Berger R, Thiesen HJ (January 1991). "Chromosomal localization of two human zinc finger protein genes, ZNF24 (KOX17) and ZNF29 (KOX26), to 18q12 and 17p13-p12, respectively". Genomics. 9 (1): 154–61. doi:10.1016/0888-7543(91)90233-5. PMID 2004757.
• Thiesen HJ (April 1990). "Multiple genes encoding zinc finger domains are expressed in human T cells". The New Biologist. 2 (4): 363–74. PMID 2288909.
• Williams AJ, Blacklow SC, Collins T (December 1999). "The zinc finger-associated SCAN box is a conserved oligomerization domain". Molecular and Cellular Biology. 19 (12): 8526–35. doi:10.1128/mcb.19.12.8526. PMC 84969. PMID 10567577.
• Han ZG, Zhang QH, Ye M, Kan LX, Gu BW, He KL, Shi SL, Zhou J, Fu G, Mao M, Chen SJ, Yu L, Chen Z (December 1999). "Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB". The Journal of Biological Chemistry. 274 (50): 35741–8. doi:10.1074/jbc.274.50.35741. PMID 10585455.
• Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, Gross HJ, Joenje H, Hoatlin ME, Mathew CG, Huber PA (October 2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport". Experimental Cell Research. 289 (2): 211–21. doi:10.1016/S0014-4827(03)00261-1. PMID 14499622.
• Gocke CB, Yu H, Kang J (February 2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates". The Journal of Biological Chemistry. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.
• Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (January 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
• Zhao DX, Ding ZC, Liu YQ, Huang ZX (May 2007). "Overexpression and purification of single zinc finger peptides of human zinc finger protein ZNF191". Protein Expression and Purification. 53 (1): 232–7. doi:10.1016/j.pep.2006.12.009. PMID 17270462.

External links

• ZNF24+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.