ZNF364

RING finger protein 115 is a protein, that in humans, is encoded by the RNF115 gene.

RNF115
Identifiers
Aliases	RNF115, BCA2, ZNF364, ring finger protein 115, ZFP364, RABRING7
External IDs	MGI: 1915095; HomoloGene: 69167; GeneCards: RNF115; OMA:RNF115 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q21.1 Start 145,738,868 bp End 145,824,095 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 F2.1 Start 96,634,980 bp End 96,698,954 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in glutes right ventricle Skeletal muscle tissue of rectus abdominis triceps brachii muscle Skeletal muscle tissue of biceps brachii paraflocculus of cerebellum tail of epididymis myocardium vastus lateralis muscle myocardium of left ventricle Top expressed in soleus muscle substantia nigra vastus lateralis muscle barrel cortex intercostal muscle motor neuron facial motor nucleus trigeminal ganglion tibialis anterior muscle conjunctival fornix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity transferase activity Cellular component cytoplasm cytosol Biological process protein K63-linked ubiquitination protein K48-linked ubiquitination ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway negative regulation of epidermal growth factor receptor signaling pathway protein ubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process protein autoubiquitination protein polyubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27246 67845 Ensembl ENSG00000265491 ENSMUSG00000028098 UniProt Q9Y4L5 Q9D0C1 RefSeq (mRNA) NM_014455 NM_026406 RefSeq (protein) NP_055270 NP_080682 Location (UCSC) Chr 1: 145.74 – 145.82 Mb Chr 3: 96.63 – 96.7 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Burger A, Amemiya Y, Kitching R, Seth AK (2006). "Novel RING E3 ubiquitin ligases in breast cancer". Neoplasia. 8 (8): 689–95. doi:10.1593/neo.06469. PMC 1601945. PMID 16925951.
• Sakane A, Hatakeyama S, Sasaki T (2007). "Involvement of Rabring7 in EGF receptor degradation as an E3 ligase". Biochem. Biophys. Res. Commun. 357 (4): 1058–64. doi:10.1016/j.bbrc.2007.04.052. PMID 17462600.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Burger AM, Gao Y, Amemiya Y, et al. (2006). "A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer". Cancer Res. 65 (22): 10401–12. doi:10.1158/0008-5472.CAN-05-2103. PMID 16288031.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Mizuno K, Kitamura A, Sasaki T (2004). "Rabring7, a novel Rab7 target protein with a RING finger motif". Mol. Biol. Cell. 14 (9): 3741–52. doi:10.1091/mbc.E02-08-0495. PMC 196564. PMID 12972561.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.