ZNF593

Zinc finger protein 593 is a protein that in humans is encoded by the ZNF593 gene.

ZNF593
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZR9
Identifiers
Aliases	ZNF593, ZT86, zinc finger protein 593
External IDs	OMIM: 616698; MGI: 1915290; HomoloGene: 41070; GeneCards: ZNF593; OMA:ZNF593 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1p36.11 Start 26,169,908 bp End 26,170,873 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 D2.3 Start 133,970,600 bp End 133,972,903 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle muscle of thigh body of pancreas right lobe of liver mucosa of transverse colon body of stomach glutes apex of heart gonad Skeletal muscle tissue of rectus abdominis Top expressed in Paneth cell endothelial cell of lymphatic vessel lumbar spinal ganglion hair follicle epithelium of lens primitive streak condyle seminal vesicula mesenteric lymph nodes fossa More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding metal ion binding nucleic acid binding acyl binding acyl carrier activity phosphopantetheine binding ribosomal large subunit binding zinc ion binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleolus nucleus cytosol preribosome, large subunit precursor Biological process regulation of transcription, DNA-templated transcription, DNA-templated ribosomal large subunit export from nucleus lipid A biosynthetic process positive regulation of transcription by RNA polymerase II negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding fatty acid biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51042 68040 Ensembl ENSG00000142684 ENSMUSG00000028840 UniProt O00488 Q9DB42 RefSeq (mRNA) NM_015871 NM_024215 RefSeq (protein) NP_056955 NP_077177 Location (UCSC) Chr 1: 26.17 – 26.17 Mb Chr 4: 133.97 – 133.97 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• ZNF593+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.