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Zhankuic acids are sterols isolated from the fungus Taiwanofungus camphoratus.[1] Zhankuic acid C possesses in vitro anti-inflammatory properties due to its role as a selective TLR4/MD-2 antagonist.[2]
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Zhankuic acid A -
Zhankuic acid B -
Zhankuic acid C
References
edit- ^ Lin, Ming-Kuem; Lee, Meng-Shiou; Chang, Wen-Te; Chen, Hsing-Yu; Chen, Jin-Fu; Li, Yi-Rong; Lin, Chi-Chen; Wu, Tian-Shung (2015). "Immunosuppressive effect of zhankuic acid C from Taiwanofungus camphoratus on dendritic cell activation and the contact hypersensitivity response". Bioorganic & Medicinal Chemistry Letters. 25 (20): 4637–4641. doi:10.1016/j.bmcl.2015.08.038. PMID 26338360.
- ^ Chen, Y.-F; Shiau, A.-L; Wang, S.-H; Yang, J.-S; Chang, S.-J; Wu, C.-L; Wu, T.-S (2014). "Zhankuic Acid A Isolated from Taiwanofungus camphoratus Is a Novel Selective TLR4/MD-2 Antagonist with Anti-Inflammatory Properties". The Journal of Immunology. 192 (6): 2778–2786. doi:10.4049/jimmunol.1301931. PMC 3948111. PMID 24532584.
External links
edit- Zhankuic acid A - PubChem
- Zhankuic acid A - ChemSpider
- Zhankuic acid B - PubChem
- Zhankuic acid B - ChemSpider
- Zhankuic acid C - PubChem
- Zhankuic acid C - ChemSpider
- Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models
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