Zinc finger protein basonuclin-2

Zinc finger protein basonuclin-2 is a protein that in humans is encoded by the BNC2 gene.[5][6] BNC2 has recently been shown to influence skin pigmentation levels in Europeans.[7] Genomic region spanning the BNC2 gene has 60% Neanderthal DNA sequence.[8]

BNC2
Identifiers
AliasesBNC2, BSN2, basonuclin 2, LUTO
External IDsOMIM: 608669; MGI: 2443805; HomoloGene: 18243; GeneCards: BNC2; OMA:BNC2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017637
NM_001317939
NM_001317940

NM_172870
NM_001369081
NM_001369082
NM_001369083
NM_001369084

RefSeq (protein)

NP_001304868
NP_001304869
NP_060107

NP_766458
NP_001356010
NP_001356011
NP_001356012
NP_001356013

Location (UCSC)Chr 9: 16.41 – 16.87 MbChr 4: 84.19 – 84.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173068Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028487Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. (Jan 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nature Genetics. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  6. ^ "Entrez Gene: BNC2 basonuclin 2".
  7. ^ Jacobs LC, Wollstein A, Lao O, Hofman A, Klaver CC, Uitterlinden AG, Nijsten T, Kayser M, Liu F (Feb 2013). "Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans". Human Genetics. 132 (2): 147–58. doi:10.1007/s00439-012-1232-9. PMID 23052946. S2CID 6057298.
  8. ^ Vattathil S, Akey JM (Oct 2015). "Small Amounts of Archaic Admixture Provide Big Insights into Human History". Cell. 163 (2): 281–4. doi:10.1016/j.cell.2015.09.042. PMID 26451479.

Further reading

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