Zinc transporter ZIP4

SLC39A4
Identifiers
Aliases	SLC39A4, AEZ, AWMS2, ZIP4, solute carrier family 39 member 4
External IDs	OMIM: 607059; MGI: 1919277; HomoloGene: 15638; GeneCards: SLC39A4; OMA:SLC39A4 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	144,416,844 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	76,501,584 bp
RNA expression pattern
	Top expressed in
	duodenum; ; mucosa of transverse colon; ; human kidney; ; renal cortex; ; body of stomach; ; left lobe of thyroid gland; ; fundus; ; right ovary; ; right lobe of thyroid gland; ; skin of abdomen;
	Top expressed in
	jejunum; ; duodenum; ; yolk sac; ; ileum; ; choroid plexus of fourth ventricle; ; epithelium of small intestine; ; intestinal villus; ; left lobe of liver; ; right lung lobe; ; left colon;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion transmembrane transporter activity; zinc ion transmembrane transporter activity;
Cellular component	integral component of membrane; endosome; recycling endosome membrane; plasma membrane; membrane; integral component of plasma membrane; cytoplasmic vesicle; apical plasma membrane;
Biological process	metal ion transport; zinc ion transport; ion transport; zinc ion import across plasma membrane; transmembrane transport; signal transduction; cellular zinc ion homeostasis; cellular response to zinc ion starvation;
	Sources:Amigo / QuickGO
Orthologs
	55630
	72027
	ENSG00000147804; ENSG00000285243
	ENSMUSG00000063354
	Q6P5W5
	Q78IQ7
	NM_001280557; NM_017767; NM_130849; NM_001374839
	NM_028064
	NP_001267486; NP_060237; NP_570901; NP_001361768
	NP_082340
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. It is associated with acrodermatitis enteropathica.^[5]