2021 Open Città della Disfida – Singles

Gianluca Mager was the defending champion but chose not to defend his title.

Singles
2021 Open Città della Disfida
Champion	Giulio Zeppieri
Runner-up	Flavio Cobolli
Score	6–1, 3–6, 6–3

Main article: 2021 Open Città della Disfida

Giulio Zeppieri won the title after defeating Flavio Cobolli 6–1, 3–6, 6–3 in the final.

Seeds

1. Andrej Martin (second round)
2. Juan Manuel Cerúndolo (first round, retired)
3. Jay Clarke (first round)
4. Tim van Rijthoven (second round)
5. Matteo Viola (first round)
6. Jack Draper (first round)
7. Riccardo Bonadio (first round)
8. Tseng Chun-hsin (semifinals)

Draw

Key

• Q = Qualifier
• WC = Wild card
• LL = Lucky loser
• Alt = Alternate
• SE = Special exempt
• PR = Protected ranking
• ITF = ITF entry
• JE = Junior exempt
• w/o = Walkover
• r = Retired
• d = Defaulted
• SR = Special ranking

Finals

	Semifinals							Final
		Thiago Agustín Tirante	1	6	5
		Flavio Cobolli	6	1	7
									Flavio Cobolli	1	6	3
									Giulio Zeppieri	6	3	6
	8	Tseng Chun-hsin	6	2	3
		Giulio Zeppieri	3	6	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	A Martin	4	6	6
	WC	J Berrettini	6	2	1			1	A Martin	63	2
		TA Tirante	6	4	6				TA Tirante	77	6
		P Chrysochos	1	6	2											TA Tirante	6	6
	Alt	F Forti	2	2											Q	N Álvarez	2	2
		R Quiroz	6	6					R Quiroz	5	4
	Q	N Álvarez	4	77	7			Q	N Álvarez	7	6
	7	R Bonadio	6	65	5																		TA Tirante	1	6	5
	4	T van Rijthoven	7	6																			F Cobolli	6	1	7
	WC	Emiliano Maggioli	5	4				4	T van Rijthoven	1	2
		P Kotov	2	6	2				F Cobolli	6	6
		F Cobolli	6	4	6											F Cobolli	6	6
	PR	Jeremy Jahn	1r													A Dougaz	3	3
		P Krstin	5						P Krstin	2	2
		A Dougaz	6	6					A Dougaz	6	6
	6	J Draper	3	2

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	8	C-h Tseng	6	0
	Q	R Harrison	1	0r				8	C-h Tseng	5	6	6
	WC	L Nardi	6	6				WC	L Nardi	7	2	4
		M Jaziri	3	1											8	C-h Tseng	6	6
		P Sakamoto	64	63											Q	A Vavassori	4	4
		N Mejía	77	77					N Mejía	3	64
	Q	A Vavassori	6	6				Q	A Vavassori	6	77
	3	J Clarke	3	4																		8	C-h Tseng	6	2	3
	5	M Viola	2	5																			G Zeppieri	3	6	6
	Q	C Rodríguez	6	7				Q	C Rodríguez	4	4
		J Ocleppo	6	6					J Ocleppo	6	6
		J Sels	4	3												J Ocleppo	7	3	2
		G Zeppieri	7	6												G Zeppieri	5	6	6
		T Skatov	5	0					G Zeppieri	6	6
		A Arnaboldi	6	2	5				A Arnaboldi	3	2
	2	JM Cerúndolo	1	6	2r

External links

• Main draw
• Qualifying draw