3-hydroxyacyl-CoA dehydratase 2

3-hydroxyacyl-CoA dehydratase 2 is a protein that in humans is encoded by the HACD2 gene. [5]

HACD2
Identifiers
AliasesHACD2, PTPLB, 3-hydroxyacyl-CoA dehydratase 2
External IDsOMIM: 615939; MGI: 1918007; HomoloGene: 23409; GeneCards: HACD2; OMA:HACD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001329783
NM_001329784
NM_001329786
NM_001329787
NM_198402

NM_023587

RefSeq (protein)

NP_001316712
NP_001316713
NP_001316715
NP_001316716
NP_940684

NP_076076

Location (UCSC)Chr 3: 123.49 – 123.59 MbChr 16: 34.84 – 34.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000206527Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035376Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: 3-hydroxyacyl-CoA dehydratase 2". Retrieved 2017-09-22.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.