ABI3BP

ABI family member 3 binding protein is a protein that in humans is encoded by the ABI3BP gene.

ABI3BP
Identifiers
Aliases	ABI3BP, NESHBP, TARSH, ABI family member 3 binding protein
External IDs	OMIM: 606279; HomoloGene: 137312; GeneCards: ABI3BP; OMA:ABI3BP - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3q12.2 Start 100,749,156 bp End 100,993,515 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in decidua synovial joint Achilles tendon vena cava skin of hip epithelium of colon saphenous vein superficial temporal artery parietal pleura urethra n/a More reference expression data BioGPS n/a
Gene ontology Molecular function glycosaminoglycan binding heparin binding collagen binding extracellular matrix structural constituent Cellular component extracellular matrix interstitial matrix extracellular space extracellular region collagen-containing extracellular matrix Biological process extracellular matrix organization positive regulation of cell-substrate adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25890 n/a Ensembl ENSG00000154175 n/a UniProt Q7Z7G0 n/a RefSeq (mRNA) NM_015429 NM_001349329 NM_001349330 NM_001349331 NM_001349332 NM_001365642 NM_001365643 NM_001375547 NM_001375549 NM_001375550 NM_001377332 n/a RefSeq (protein) NP_056244 NP_001336258 NP_001336259 NP_001336260 NP_001336261 NP_001352571 NP_001352572 NP_001362476 NP_001362478 NP_001362479 NP_001364261 n/a Location (UCSC) Chr 3: 100.75 – 100.99 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Further reading

• Uekawa N, Terauchi K, Nishikimi A, Shimada J, Maruyama M (2005). "Expression of TARSH gene in MEFs senescence and its potential implication in human lung cancer". Biochem. Biophys. Res. Commun. 329 (3): 1031–8. doi:10.1016/j.bbrc.2005.02.068. PMID 15752759.
• Terauchi K, Shimada J, Uekawa N, Yaoi T, Maruyama M, Fushiki S (2006). "Cancer-associated loss of TARSH gene expression in human primary lung cancer". J. Cancer Res. Clin. Oncol. 132 (1): 28–34. doi:10.1007/s00432-005-0032-1. PMID 16205947. S2CID 25189707.
• Latini FR, Hemerly JP, Oler G, Riggins GJ, Cerutti JM (2008). "Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion". Endocr. Relat. Cancer. 15 (3): 787–99. doi:10.1677/ERC-08-0079. PMC 2742300. PMID 18559958.
• Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
• Wakoh T, Uekawa N, Terauchi K, Sugimoto M, Ishigami A, Shimada J, Maruyama M (2009). "Implication of p53-dependent cellular senescence related gene, TARSH in tumor suppression". Biochem. Biophys. Res. Commun. 380 (4): 807–12. doi:10.1016/j.bbrc.2009.01.171. PMID 19338757.
• Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Schulze T, Potash JB, Zandi PP, Willour VL, Penninx BW, Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M, Craddock N, Sklar P, Smoller JW (2010). "Genome-wide association study of suicide attempts in mood disorder patients". Am J Psychiatry. 167 (12): 1499–507. doi:10.1176/appi.ajp.2010.10040541. PMC 3795390. PMID 21041247.