Ammasi Periasamy is an Indian American biophysicist who is a professor at the University of Virginia. He works on light microscopy, including the molecular imaging of living cells. He has developed a range of imaging systems, including confocal, multi-photon and fluorescence-lifetime imaging microscopy base devices.
Ammasi Periasamy | |
|---|---|
| Alma mater | University of Madras Indian Institute of Technology |
| Scientific career | |
| Institutions | University of Washington University of Virginia |
| Thesis | Molecular imaging : FRET microscopy and spectroscopy (1984) |
Early life and education
editPeriasamy was born in India. He trained at the University of Madras and the Indian Institutes of Technology.[1] After earning his doctorate in 1984, Periasamy moved to the University of Washington for a postdoctoral research position.[1]
Research and career
editPeriasamy founded the W. M. Keck Centre for Cellular Imaging. His research considers the development of microscopy for imaging of living cells. He has designed various advanced modalities, including multi-photon and confocal approaches. In particular, Periasamy is interested in understanding protein-protein interactions and the monitoring of physical parameters in cancer cells.[2] Periasamy was one of the first researchers to demonstrate fluorescence-lifetime imaging microscopy (FLIM) and fluorescence lifetime redox ratio (FLIRR).[3][4][5]
Selected publications
edit- Rajesh Babu Sekar; Ammasi Periasamy (1 March 2003). "Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations". Journal of Cell Biology. 160 (5): 629–633. doi:10.1083/JCB.200210140. ISSN 0021-9525. PMC 2173363. PMID 12615908. Wikidata Q24673219.
- Horst Wallrabe; Ammasi Periasamy (1 February 2005). "Imaging protein molecules using FRET and FLIM microscopy". Current Opinion in Biotechnology. 16 (1): 19–27. doi:10.1016/J.COPBIO.2004.12.002. ISSN 0958-1669. PMID 15722011. Wikidata Q30435991.
- Masilamani Elangovan; Horst Wallrabe; Ye Chen; Richard N Day; Margarida Barroso; Ammasi Periasamy (1 January 2003). "Characterization of one- and two-photon excitation fluorescence resonance energy transfer microscopy". Methods. 29 (1): 58–73. doi:10.1016/S1046-2023(02)00283-9. ISSN 1046-2023. PMID 12543072. Wikidata Q33185799.
References
edit- ^ a b "| Department of Biology, U.Va". bio.as.virginia.edu. Retrieved 2023-01-27.
- ^ Periasamy, Ammasi (2006-04-14), "Cellular Imaging", in Webster, John G. (ed.), Encyclopedia of Medical Devices and Instrumentation, Hoboken, NJ, USA: John Wiley & Sons, Inc., pp. emd327, doi:10.1002/0471732877.emd327, ISBN 978-0-471-73287-7, retrieved 2023-01-27
- ^ "Ammasi Periasamy". www.leica-microsystems.com. Retrieved 2023-01-27.
- ^ FLIM MICROSCOPY IN BIOLOGY AND MEDICINE. [S.l.]: CRC PRESS. 2020. ISBN 978-0-367-57730-8. OCLC 1156990580.
- ^ "At UVA's Keck Center, Researchers Peer Deep Into Inner Workings of Cells". UVA Today. 2017-12-14. Retrieved 2023-01-27.
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