Asim K. Duttaroy is an Indian-born American medical scientist who, since 2001, has worked as a Professor at the Faculty of Medicine, University of Oslo, Norway.[1] He was born in Gopinagar (Gangnapur), Nadia district, West Bengal, India.[citation needed]
Asim Kanti Duttaroy | |
|---|---|
 | |
| Born | July 8, 1955 |
| Website | www |
Duttaroy is the author of over 450 research papers and book chapters, has authored or edited several books, and holds several international patents.[2] His research contributions have led to several industrial developments worldwide, such as Provexis.[citation needed][3] Duttaroy, while he worked as Professor (1990-2001) at the Rowett Research Institute at the University of Aberdeen, Scotland, United Kingdom, discovered that an extract from tomato had a positive effect in the prevention of blood platelet aggregation.[4][5][6] Hyperactive platelets are important mediators of atherogenesis. In addition to their roles in thrombosis, antiplatelet drugs are not suitable for use where the risk of a cardiovascular event is relatively low. Therefore, it is essential to find alternative, safe antiplatelet inhibitors for the vulnerable population with hyperactive platelets in order to reduce the risk of cardiovascular disease. Potent antiplatelet factors were identified in water-soluble tomato extract (Fruitflow®), significantly inhibiting platelet aggregation.
Another area of his research has been the investigation of the fatty acid transport system in human placenta and its roles in the placental preferential transfer of critically important nutrients such as docosahexaenoic acid,22:6n-3 (DHA) and arachidonic acid,20:4n-6 (ARA) from the mother to the fetus.[7] He demonstrated the presence of several plasma membrane-located transport/binding proteins, such as fatty acid translocase (FAT/CD36), plasma membrane fatty acid binding protein (FABPpm), fatty acid transport protein (FATP), and intracellular FABPs, in the human placenta. He identified the placental-specific FABPpm is mainly responsible for the preferential placental transport of DHA and ARA from the mother to support fetal brain growth during the third trimester.
Duttaroy serves as Editor-In-Chief of the peer-reviewed journal Food & Nutrition Research,[8] which has an Impact factor of 3.89 (2020).[citation needed] Duttaroy serves on the editorial boards of several other journals, including Prostaglandins Leukotrienes and Essential Fatty Acids,[9] Nutrients,[10] and European Journal of Lipid Science and Technology.[11]
Legacy
editDuttaroy’s research focuses on how the placenta transports maternal plasma DHA and ARA to the fetus.[12][13][14] The fetal brain development in utero is critically dependent on the maternal supply of these fatty acids in the utero.[15][16][17][18] His studies have been documented through several articles.[19][20] Besides, his articles have drawn many citations (Google Scholar PubMed). His other research area is cardioprotective factors in fruits and vegetables. He has discovered the anti-platelet factors from tomatoes.[21] This discovery made by him is now widely known as Fruitflow.[22][23] In 2009, Fruitflow® became the first product in Europe to obtain an approved, proprietary health claim under Article 13(5) of the European Health Claims Regulation 1924/2006 on nutrition and health claims made on foods.[24] The EU Commission authorized the health claim “water-soluble tomato concentrate (WSTC) I and II help maintain normal platelet aggregation, which contributes to healthy blood flow.”.[25][26] Fruitflow® is now widely available in different countries worldwide.[27]
Books
edit- Duttaroy, Asim K.; Spener, Friedrich (October 2003). Cellular Proteins and Their Fatty Acids in Health and Disease. Wiley-VCH, Germany. pp. 1–478. ISBN 978-3-527-60528-6.
- Duttaroy, Asim K.; Basak, Sanjay (October 2016). Human Placental Trophoblasts: Impact of Maternal Nutrition. CRC Press, USA. pp. 1–437. ISBN 978-1-4822-5428-0.
- Duttaroy, Asim K.; Basak, Sanjay (October 2017). Early Nutrition and Lifestyle Factors: Effects on First Trimester Placenta. Springer. pp. 1–159. doi:10.1007/978-3-319-38804-5. ISBN 978-3-319-38802-1.
- Duttaroy, Asim K. (June 2018). Nutraceuticals and Human Blood Platelet Function: Applications in Cardiovascular Health. Wiley. pp. 1–300. ISBN 978-1-119-37601-9.Duttaroy, Asim K. (July 2021). Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease. Elsevier. pp. 1–462. ISBN 978-0-128-22405-2.
- Duttaroy, Asim K. (July 2021). Maternal DHA Impact on Child Neurodevelopment. MPDI. pp. 1–115. ISBN 978-3-0365-1615-8.
- Pathak, Surajit; Banerjee, Antara; Duttaroy, Asim K. (July 2023). Evidence-based Functional Foods for Prevention of Age-related Diseases. Springer Singapore. pp. 1–371. doi:10.1007/978-981-99-0534-8. ISBN 978-981-99-0533-1.
- Duttaroy, Asim K.; Mallick, Rahul (July 2024). Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling From Lab Bench to Clinical Perspective. Elsevier. pp. 1–500. ISBN 9780323995702.
- Duttaroy, Asim K. (October 2024). Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease From Basic Science to Clinical Application. Elsevier. pp. 1–400. ISBN 9780323957007.
References
edit- ^ "Asim K. Duttaroy- Institute of Basic Medical Sciences". uio.no. Retrieved 28 June 2016.
- ^ "Research Gate: Asim K. Duttaroy". uio.no. Retrieved 6 August 2016.
- ^ "Provexis- Home Page".
- ^ "Recent Achievements, Rowett Institute". Retrieved 21 August 2018.
- ^ O'Kennedy, N; Crosbie, L; Van Lieshout, M; Broom, J. I.; Webb, D. J.; Duttaroy, A. K. (2006). "Effects of antiplatelet components of tomato extract on platelet function in vitro and ex vivo: A time-course cannulation study in healthy humans". The American Journal of Clinical Nutrition. 84 (3): 570–9. doi:10.1093/ajcn/84.3.570. PMID 16960171.
- ^ Duttaroy, Asim K. "Fruitflow". Rowett Institute of Nutrition and Health - University of Aberdeen. Retrieved 22 September 2016.
- ^ Duttaroy, A (2009). "Transport of fatty acids across the human placenta: A review". Progress in Lipid Research. 48 (1): 52–61. doi:10.1016/j.plipres.2008.11.001. PMID 19041341.
- ^ "Editorial Team". foodandnutritionresearch.net. Retrieved 28 June 2016.
- ^ "Editorial Team". Prostaglandins Leukotrienes and Essential Fatty Acids. Retrieved 19 July 2016.
- ^ "Editorial Team". Nutrients. Retrieved 5 September 2018.
- ^ "Editorial Team". European Journal of Lipid Science and Technology. doi:10.1002/(ISSN)1438-9312. hdl:2158/1155277. Retrieved 5 September 2018.
- ^ Dutta-Roy, Asim K (2000-01-01). "Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta". The American Journal of Clinical Nutrition. 71 (1): 315s–322s. doi:10.1093/ajcn/71.1.315s. ISSN 0002-9165. PMID 10617989.
- ^ Basak, Sanjay; Mallick, Rahul; Banerjee, Antara; Pathak, Surajit; Duttaroy, Asim K. (2021-06-16). "Maternal Supply of Both Arachidonic and Docosahexaenoic Acids Is Required for Optimal Neurodevelopment". Nutrients. 13 (6): 2061. doi:10.3390/nu13062061. ISSN 2072-6643. PMC 8234848. PMID 34208549.
- ^ Duttaroy, Asim K.; Basak, Sanjay (2020-04-01). "Maternal dietary fatty acids and their roles in human placental development". Prostaglandins, Leukotrienes and Essential Fatty Acids. 155: 102080. doi:10.1016/j.plefa.2020.102080. hdl:10852/83730. PMID 32120190. S2CID 211833726.
- ^ Duttaroy, Asim (2021-06-27). "Special Issue "Maternal DHA Impact on Child Neurodevelopment"". Nutrients. 13 (7): 2209. doi:10.3390/nu13072209. ISSN 2072-6643. PMC 8308222. PMID 34199063.
- ^ Ogundipe, E.; Tusor, N.; Wang, Y.; Johnson, M.R.; Edwards, A.D.; Crawford, M.A. (2018-11-01). "Randomized controlled trial of brain specific fatty acid supplementation in pregnant women increases brain volumes on MRI scans of their newborn infants". Prostaglandins, Leukotrienes and Essential Fatty Acids. 138: 6–13. doi:10.1016/j.plefa.2018.09.001. PMID 30392581. S2CID 53215840.
- ^ Basak, Sanjay; Mallick, Rahul; Duttaroy, Asim K. (2020-11-25). "Maternal Docosahexaenoic Acid Status during Pregnancy and Its Impact on Infant Neurodevelopment". Nutrients. 12 (12): 3615. doi:10.3390/nu12123615. ISSN 2072-6643. PMC 7759779. PMID 33255561.
- ^ Mallick, Rahul; Basak, Sanjay; Duttaroy, Asim K. (2019-12-01). "Docosahexaenoic acid, 22:6n-3: Its roles in the structure and function of the brain". International Journal of Developmental Neuroscience. 79 (1): 21–31. doi:10.1016/j.ijdevneu.2019.10.004. ISSN 0736-5748. PMID 31629800. S2CID 204761373.
- ^ "Professor Asim K. Duttaroy". scholar.google.com. Retrieved 2021-11-16.
- ^ MedicineProfessor, Asim K. DuttaroyUniversity of Oslo · Faculty of. "Asim DUTTAROY | Professor | Professor | University of Oslo, Oslo | Faculty of Medicine". ResearchGate. Retrieved 2021-11-16.
- ^ Dutta-Roy, Asim K.; Crosbie, Lynn; Gordon, Margaret J. (2001-01-01). "Effects of tomato extract on human platelet aggregation in vitro". Platelets. 12 (4): 218–227. doi:10.1080/09537100120058757. ISSN 0953-7104. PMID 11454256. S2CID 218867515.
- ^ O’Kennedy, Niamh; Raederstorff, Daniel; Duttaroy, Asim K. (2017-03-01). "Fruitflow®: the first European Food Safety Authority-approved natural cardio-protective functional ingredient". European Journal of Nutrition. 56 (2): 461–482. doi:10.1007/s00394-016-1265-2. ISSN 1436-6207. PMC 5334395. PMID 27388464.
- ^ "Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation [1] | EFSA". www.efsa.europa.eu. 28 May 2009. doi:10.2903/j.efsa.2009.1101. Retrieved 2021-11-15.
- ^ "Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation [1] | EFSA". www.efsa.europa.eu. 28 May 2009. doi:10.2903/j.efsa.2009.1101. Retrieved 2021-11-15.
- ^ O’Kennedy, Niamh; Raederstorff, Daniel; Duttaroy, Asim K. (2017-03-01). "Fruitflow®: the first European Food Safety Authority-approved natural cardio-protective functional ingredient". European Journal of Nutrition. 56 (2): 461–482. doi:10.1007/s00394-016-1265-2. ISSN 1436-6207. PMC 5334395. PMID 27388464.
- ^ "Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation [1] | EFSA". www.efsa.europa.eu. 28 May 2009. doi:10.2903/j.efsa.2009.1101. Retrieved 2021-11-15.
- ^ "Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation [1] | EFSA". www.efsa.europa.eu. 28 May 2009. doi:10.2903/j.efsa.2009.1101. Retrieved 2021-11-15.