Guanine nucleotide-binding protein G(t) subunit alpha-1 is a protein that in humans is encoded by the GNAT1 gene.[5]

GNAT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGNAT1, CSNBAD3, GBT1, GNATR, CSNB1G, G protein subunit alpha transducin 1, HG1F
External IDsOMIM: 139330; MGI: 95778; HomoloGene: 20084; GeneCards: GNAT1; OMA:GNAT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000172
NM_144499

NM_008140

RefSeq (protein)

NP_000163
NP_653082

NP_032166

Location (UCSC)Chr 3: 50.19 – 50.2 MbChr 9: 107.55 – 107.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. Alternative splicing of this gene results in two transcript variants.[5]

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000114349Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034837Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1".

Further reading

edit
edit
  • Overview of all the structural information available in the PDB for UniProt: P11488 (Guanine nucleotide-binding protein G(t) subunit alpha-1) at the PDBe-KB.