major histocompatibility complex (human), class I, B73
| ||
| Alleles | B*7301 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*7301 | |
| Locus | chr.6 6p21.31 | |
HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)
Serotype
editB*73:01 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*55:03.[3]
| B*73 | B73 | Other | Sample |
| allele | % | % | size (N) |
| 7301 | 22 | 69 | 106 |
B*7301 frequencies
edit| freq | ||
| ref. | Population | (%) |
| [5] | Parsi (Karachi, Pakistan) | 4.9 |
| [5] | United Arab Emirates | 2.0 |
| [5] | Italy | 2.0 |
| [5] | Seri (Sonora, Mexico) | 1.5 |
| [5] | Purépecha (Michoacán, Mexico) | 1.5 |
| [5] | Jews (Israel) (*2 studies) | 1.2 |
| [5] | Beti (Cameroon) | 1.1 |
| [5] | Casablanca (Morocco) | 0.9 |
| [5] | Tbilisi (Georgia) | 0.9 |
| [5] | Mossi (Burkina Faso) | 0.9 |
| [5] | Bulgaria | 0.9 |
| [5] | Sudanese | 0.8 |
| [5] | Tuva (Russia) (2) | 0.8 |
| [5] | Oman | 0.8 |
| [5] | Bamileke (Cameroon) | 0.6 |
| [5] | Pathan (Pakistan) | 0.5 |
| [5] | Khalkha (Mongolia) | 0.5 |
| [5] | Druse Arabs (Israel) | 0.5 |
| [5] | Baloch (Iran) | 0.5 |
| [5] | Manchester (England) | 0.5 |
| [5] | Algeria (1) | 0.5 |
| [5] | Turkey | 0.4 |
| [5] | Amman (Jordan) | 0.3 |
| [5] | Shona (Harare, Zimbabwe) | 0.2 |
| [5] | Republic of Macedonia | 0.2 |
| [5] | Nandi (Kenya) | 0.2 |
| [5] | Luo (Kenya) | 0.2 |
| [5] | Campania (Italy) | 0.2 |
| [5] | Greece | 0.2 |
References
edit- ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- ^ Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. doi:10.1111/j.1744-313X.1995.tb00237.x. PMID 8547229.
- ^ Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.