major histocompatibility complex (human), class I, B78
Alleles B*7801
B*7802
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7801
EBI-HLA B*7802
Locus chr.6 6p21.31

HLA-B78 (B78) is an HLA-B serotype. The serotype identifies the more common HLA-B*78 gene products.[1] B78 is more common in West and North Africa, but is also scattered at low frequencies in parts of Asia. (For terminology help see: HLA-serotype tutorial)

Serotype

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B78 serotype recognition of some HLA B*78 allele-group gene products[2]
B*78 B78 other Sample
allele % % size (N)
7801 41 48 210

Allele frequencies

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HLA B*7801 frequencies
freq
ref. Population (%)
[3] Fulani (Burkina Faso) 8.2
[3] Bandiagara (Mali) 6.9
[3] Niokholo Mandinka (Senegal) 5.3
[3] Mossi (Burkina Faso) 2.8
[3] Guinea Bissau 2.3
[3] Akan Adiopodoume (Ivory Coast) 2.3
[3] Tunis (Tunisia) 2.3
[3] Berber (Morocco) 1.4
[3] Rimaibe (Burkina Faso) 1.1
[3] New Delhi (India) 0.8
[3] Lisu (Yunnan, China) 0.7
[3] Beti (Cameroon) 0.6
[3] Majorca & Minorca (Spain) 0.6
[3] Gypsy (E. Andalusia, Spain) 0.5
[3] Tunisia 0.5
[3] Romanian 0.3
[3] Northeast Thailand 0.2
[3] Tibet (China) 0.6
'
HLA B*7802 frequencies
[3] Svans (Georgia) 0.6
[3] Arab Druse (Israel) 0.5
[3] Delhi (India) 0.5
[3] Southern Han (China) 0.2
[3] Beijing (China) 0.1

References

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  1. ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. ^ derived from IMGT/HLA
  3. ^ a b c d e f g h i j k l m n o p q r s t u v w Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.