In molecular biology, the hepatitis A virus cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase in hepatitis A virus (HAV). It is larger than the CREs found in related Picornavirus species, but is thought to be functionally similar. It is thought to be involved in uridylylation of VPg.[1]
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edit- ^ Yang, Y; Yi, M; Evans, DJ; Simmonds, P; Lemon, SM (October 2008). "Identification of a conserved RNA replication element (cre) within the 3Dpol-coding sequence of hepatoviruses". Journal of Virology. 82 (20): 10118–28. doi:10.1128/jvi.00787-08. PMC 2566277. PMID 18684812.