Max Jessner

Max Jessner
Max Jessner
Born	2 November 1887; Stolp, German Empire; (now Słupsk, Poland)
Died	27 August 1978 (aged 91); Switzerland
Nationality	German
Known for	Jessner's solution; Jessner-Kanof disease
	Medical career
Profession	Physician
Institutions	University of Breslau
Sub-specialties	Dermatology

Max Jessner (2 November 1887 – 27 August 1978)^{[citation needed]} was a German dermatologist and university professor. In 1928 he travelled to Buriat-Mongolia on an expedition to study syphilis and the effects of the anti-syphilitic drug Salvarsan. After escaping Nazi occupied Europe in the mid-1930s, he settled in New York. Jessner is remembered for the development of the chemical peel known as Jessner's solution and the description of Jessner-Kanof disease.

Early life and education

Max Jessner was born on 2 November 1887 in Stolp (now Słupsk in Poland), the son of the dermatologist and lecturer at the University of Königsberg Samuel Jessner (1859–1929).^[1] He studied medicine at the universities of Munich and Königsberg.^[2]

Jessner did his dermatological training at clinics in Breslau (now Wroclaw) under Albert Neisser.^[1]

He became assistant to Joseph Jadassohn at the University Department of Dermatology in Bern from 1912 to 1914.^[2] Following the interruption of the First World War, in which he also fought,^[3] he followed Jadassohn to the University of Breslau in 1917.^[2] After his habilitation there in 1922, he was appointed associate professor in 1926.^[4]

Career

In April 1928,^[5] Jessner travelled to Buriat-Mongolia as part of the Soviet-German Syphilis Expedition, an expedition to study syphilis and the effects of the anti-syphilitic drug Salvarsan. The mission involved eight Soviet and eight German researchers.^[2]^[5]^[6] For post-revolutionary Russia, the expedition marked an opportunity to use science to solidify political relations and improve communication. For the Germans, it was an opening to the east.^[6]^[7]

In 1931, he was appointed to Josef Jadassohn's chair.^[4] In either 1934^[4] or 1935,^[2] he was forced to resign, along with Hans Biberstein, because of his Jewish descent.^[3]^[2]^[8] His successor was Heinrich Gottron who was favoured by the National Socialist regime.^[4] Biberstein later became professor of dermatology at New York University^[4] like many other dermatologists who escaped Nazi-occupied Europe by travelling to North America.^[9]

Jessner first emigrated to Switzerland in 1935,^[4] then in 1941 to New York,^[10] where he was reunited with Biberstein.^[11] At first, he found work at the New York Postgraduate Medical School and later, he was appointed to the teaching staff of New York University School of Medicine's Skin and Cancer Unit.^[4]

Research

Also known as the Coombe's formula,^[12] Jessner developed it to form Jessner's solution,^[13] a liquid peeling treatment for hyperkeratotic epidermal lesions, containing salicyclic acid, resorcinol, and lactic acid in 95% ethanol, and works by breaking intracellular bridges between keratinocytes. He reduced the concentration of resorcinol due to its associated allergic contact dermatitis, irritant contact dermatitis and skin discolouration. Modified Jessner's solutions, replacing resorcinol with TCA are available.^[14]

In New York, he was assisted, like many others, by Marion Sulzberger at the New York Skin and Cancer Unit.^[15] It was here that in 1953, with Kanof, he became renowned for the description of Jessner-Kanof disease, a lymphocytic infiltrate of the skin where the lesions were asymptomatic, presenting as red spots or plaques with spontaneous recurrences.^[2]^[16]

Later life

After retiring, Jessner moved back to Switzerland, where he died on 27 June 1978.^{[citation needed]}^[2]

Selected publications

Clinical and Histopathalogic Aspects of Skin Cancer, Journal of Investigative Dermatology, Vol. 11, Issue 1, July 1948, pp. 91–92. doi:10.1038/jid.1948.72

References

^ ^a ^b "Jessner, Max – Altmeyers Enzyklopädie – Fachbereich Dermatologie". 15 May 2014. Retrieved 16 September 2018.
^ ^a ^b ^c ^d ^e ^f ^g ^h Białynicki-Birula, R; Maj, E (1 January 2014). "Max Jessner (1887–1978) – A prominent Wroclaw's dermatologist". 16: 83–87. {{cite journal}}: Cite journal requires |journal= (help)(subscription required)
^ ^a ^b Wolfgang Weyers (1998). Death of Medicine in Nazi Germany: Dermatology and Dermatopathology Under the Swastika. Ardor/Scribendi. pp. 75–79. ISBN 978-1-56833-121-8.
^ ^a ^b ^c ^d ^e ^f ^g Dermatology and Dermatopathology under the Swastika. Wolfgang Weyers. Derm101. Retrieved 9 September 2018.
^ ^a ^b "Lilly Library News & Notes". blogs.libraries.indiana.edu. Retrieved 16 September 2018.
^ ^a ^b Solomon, Susan Gross (1993). "The Soviet-German Syphilis Expedition to Buriat Mongolia, 1928: Scientific Research on National Minorities". Slavic Review. 52 (2): 204–232. doi:10.2307/2499920. JSTOR 2499920. S2CID 156660997.(subscription required)
^ Solomon, Susan Gross (2006). Doing Medicine Together: Germany and Russia Between the Wars. University of Toronto Press. ISBN 9780802091710.
^ Hamel, Johanna; Burgdorf, Walter H. C.; Bräuninger, Wolfgang (October 2009). "The man behind the eponym: Hans Biberstein and follicular hyperplasia overlying dermatofibroma". The American Journal of Dermatopathology. 31 (7): 710–714. doi:10.1097/DAD.0b013e3181a23b9e. ISSN 1533-0311. PMID 19633531. S2CID 7015876.
^ Holubar, Karl; Wolff, Klaus (April 1989). "The Genesis of American Investigative Dermatology from its Roots in Europe" (PDF). Klaus. 82: 14–21.
^ Jessner, Max (Bestandsbildner). Deutsche National Bibliothek. Retrieved 9 September 2018.
^ Fritz Stern (2007). Five Germanys I Have Known: A History & Memoir. Farrar, Straus and Giroux. p. 104. ISBN 978-1-4668-1922-1.
^ Deprez, Philippe (2016). Textbook of Chemical Peels, Second Edition: Superficial, Medium, and Deep Peels in Cosmetic Practice (2nd ed.). CRC Press. p. 379. ISBN 9781482223941.
^ Harold J. Brody; Harold Joseph Brody (1997). Chemical Peeling and Resurfacing. Mosby. p. 82. ISBN 978-0-8151-1261-7.
^ Grimes, Pearl E. (2012). "7. Jessner's Solution". In Tosti, Antonella; Grimes, Pearl E.; Pia De Padova, Maria (eds.). Color Atlas of Chemical Peels. Springer-Verlag Berlin Heidelberg. p. 57. ISBN 978-3-642-20269-8.
^ "British Association of Dermatologists - Dr Marion Sulzberger". www.bad.org.uk. Retrieved 10 September 2018.
^ Burgdorf, Walter H. C.; Gerami, Pedram; Yan, Albert C. (2011). "21. benign and malignant tumors". In Schachner, Lawrence A.; Hanson, Ronald C. (eds.). Pediatric Dermatology E-Book. Vol. 1 (4th ed.). Mosby Elsevier. p. 1021. ISBN 9780723435402.