NMD3

60S ribosomal export protein NMD3 is a protein that in humans is encoded by the NMD3 gene.

NMD3
Identifiers
Aliases	NMD3, CGI-07, NMD3 ribosome export adaptor
External IDs	OMIM: 611021; MGI: 2140103; HomoloGene: 6127; GeneCards: NMD3; OMA:NMD3 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3q26.1 Start 161,104,696 bp End 161,253,532 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 E1- E2 Start 69,629,318 bp End 69,663,706 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell germinal epithelium skin of thigh skin of hip parotid gland secondary oocyte amniotic fluid parietal pleura visceral pleura gingival epithelium Top expressed in embryo secondary oocyte embryo epiblast primary oocyte primitive streak zygote tail of embryo morula Paneth cell More reference expression data BioGPS n/a
Gene ontology Molecular function protein-macromolecule adaptor activity RNA binding ribosomal large subunit binding Cellular component nucleus membrane nucleolus cytoplasm nucleoplasm Biological process protein transport ribosomal large subunit export from nucleus positive regulation of RNA biosynthetic process positive regulation of protein localization to nucleolus positive regulation of protein binding transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51068 97112 Ensembl ENSG00000169251 ENSMUSG00000027787 UniProt Q96D46 Q99L48 RefSeq (mRNA) NM_015938 NM_001320227 NM_133787 RefSeq (protein) NP_001307156 NP_057022 NP_598548 Location (UCSC) Chr 3: 161.1 – 161.25 Mb Chr 3: 69.63 – 69.66 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Interactions

NMD3 has been shown to interact with XPO1.

Further reading

• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Thomas F, Kutay U (2003). "Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway". J. Cell Sci. 116 (Pt 12): 2409–19. doi:10.1242/jcs.00464. PMID 12724356.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.