Portal:Music/DateOfBirth/September 22
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- King Sunny Adé, Nigerian musician, singer and songwriter, turns 78.
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- David Coverdale, American vocalist with Deep Purple, Whitesnake, turns 73.
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- Richard Fairbrass, British singer from the band Right Said Fred, turns 71.
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- Tony DaGradi, American tenor saxophonist, turns 71.
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- Debby Boone, American vocalist, turns 68.
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- Johnette Napolitano, American bassist, songwriter, and lead vocalist for Concrete Blonde, turns 67.
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- Nick Cave, Australian vocalist with Nick Cave and the Bad Seeds, turns 67.
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- Andrea Bocelli, Renowned opera singer, turns 66.
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- Joan Jett, American rock and roll musician, turns 66.
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- Shari Belafonte, American singer and actress; daughter to Harry Belafonte, turns 66.
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- Ken Vandermark, American jazz saxophonist, turns 60.
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- Andy Cairns, guitarist and vocalist for Therapy?, turns 59.
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- Matt Sharp, American bassist for Weezer, turns 55.
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- Rah Digga, American rapper, turns 54.
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- Chesney Hawkes, Brit vocalist, turns 53.
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- Big Rube, American R&B singer with Society of Soul and Dungeon Family, turns 53.
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- Marlena Shaw (September 22, 1942 –January 19, 2024), American jazz vocalist, would have turned 82 this year.
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- Bill Smith (September 22, 1926–February 29, 2020), American composer and clarinettist, would have turned 98 this year.
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- Ray Wetzel (September 22, 1924 –August 17, 1951), American jazz trumpeter, would have turned 100 this year.
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- Rio De Gregori (September 22, 1919 –May 22, 1987), Swiss pianist, would have turned 105 this year.
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- Fletcher Smith (September 22, 1913 –August 15, 1993), American session musician; pianist who worked with Slim Gaillard, Big Maybelle, Earl Bostic, Percy Mayfield, and Stick McGhee, would have turned 111 this year.