Portal:Music/DateOfBirth/September 27
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- Mike Nock, New Zealand jazz keyboardist, turns 84.
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- Randy Bachman, Canadian guitarist with The Guess Who & Bachman-Turner Overdrive, turns 81.
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- Barbara Dickson, Scottish actress and singer, turns 77.
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- Shaun Cassidy, American singer-songwriter, turns 66.
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- Stephan Jenkins, American lead vocalist for Third Eye Blind, turns 60.
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- Mark Calderon, American R&B vocalist for Color Me Badd , turns 54.
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- Big Mike, (born Michael Barnett) American rapper for Geto Boys , turns 53.
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- Carrie Brownstein, of Sleater-Kinney, Wild Flag and Portlandia , turns 50.
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- Lee Brennan, Brit lead vocalist for 911 , turns 49.
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- Patrick Bourque, American Emerson Drive, turns 47.
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- Brad Arnold, American vocalist, 3 Doors Down, turns 46.
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- Jon McLaughlin, American singer-songwriter, turns 42.
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- Lil Wayne, (born Dwayne Michael Carter, Jr.) American rapper, turns 42.
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- Avril Lavigne, Canadian singer-songwriter and Juno Award winner, turns 40.
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- Robbie Shakespeare (September 27, 1953 –December 08, 2021), Jamaican bassist with Sly and Robbie, would have turned 71 this year.
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- Greg Ham (September 27, 1953–April 19, 2012), Australian musician with Men At Work, would have turned 71 this year.
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- Meat Loaf (September 27, 1947–January 20, 2022), (nee Marvin Lee Aday) American singer, would have turned 77 this year.
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- Peter Ecklund (September 27, 1945–April 08, 2020), American trumpeter and cornetist, would have turned 79 this year.
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- Alvin Stardust (September 27, 1942 –October 23, 2014), (nee Bernard William Jewry) Brit singer and thespian, would have turned 82 this year.
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- Guido Basso (September 27, 1937 –February 13, 2023), Canadian trumpeter and flugelhorn player, would have turned 87 this year.
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- Don Cornelius (September 27, 1936 –February 01, 2012), American music producer and host of Soul Train, would have turned 88 this year.
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- Lars Erstrand (September 27, 1936 –March 11, 2009), Swedish vibraphonist, would have turned 88 this year.
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- Ib Glindemann (September 27, 1934 –April 05, 2019), Danish bandleader and trumpeter with Stan Kenton and Stan Getz, would have turned 90 this year.
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- Red Rodney (September 27, 1927 –May 27, 1994), American jazz trumpeter, would have turned 97 this year.
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- Hank Levy (September 27, 1927 –September 18, 2001), American baritone saxophonist, would have turned 97 this year.
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- Jack Duffy (September 27, 1926 –May 19, 2016), Canadian vocalist and actor, would have turned 98 this year.
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- Bud Powell (September 27, 1924 –July 31, 1966), American jazz pianist, would have turned 100 this year.
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- Nat Shapiro (September 27, 1922 –December 18, 1983), American writer and record producer, would have turned 102 this year.
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- Sammy Benskin (September 27, 1922 –August 26, 1992), American jazz pianist, would have turned 102 this year.
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- Teddy Brannon (September 27, 1916 –February 24, 1989), American blues pianist, would have turned 108 this year.
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- Erhard Bauschke (September 27, 1912–October 07, 1945), German reed player, would have turned 112 this year.
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- Skip Hall (September 27, 1909 –November , 1980), American arranger and pianist, would have turned 115 this year.
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- Vincent Youmans (September 27, 1898 –April 05, 1946), American composer, would have turned 126 this year.
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- Joseph McCarthy (September 27, 1885 –December 18, 1943), American lyricist and composer, would have turned 139 this year.
