Talk:Genetic studies on Gujarati people

Cha gaam patels

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Chha Gam Patels of Gujarat can have up to 70% West Asian genetic contribution, mostly from Iran and Afghanistan due to the large influx of Persians into Gujarat’s coastal areas. They can have up to 20% South Asian genetics from parental Hindu populations. Diversity within Chha Gam Patel’s is large due to the marital customs. This often means there is a frequent occurrence of inherited diseases.[32]

Who comes up with this nonsense? These Hindu Patels probably do not even have 1% recent west asian ancestry.

"Harappa Ancestry Project" is not a reliable source

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Harappa Project was created independently by an unreputable person and it is not a reliable source. I think it should be removed. A145029 (talk) 17:59, 1 May 2018 (UTC)Reply

@A145029:, thank you for updating the article with new information. I know that Harappa Ancestry Project is an independent project. I also know that the creator is not genetics expert. He simply process the publicly available datasets from HapMap etc and publishes the result. One thing is clear that the dataset is true so the results are true too. This results are the only study analyzing genetic data from Gujarati people. So I have added it to the article considering that the results and datasets analyzing Gujarati people is true even if the person processing data is not genetics expert. If you can find better study analyzing genetic dataset specifically for Gujarati people, I would be happy to replace current info with it. In the scenario of lack of specific studies, we can keep current information which is trustworthy enough. Regards,--Nizil (talk) 05:52, 5 May 2018 (UTC)Reply
@Nizil Shah: Thanks for replying. I found following study Sengupta et al. (2016) Table 2 which breaks down Gujaratis DNA.[1] Since it is from a research study I think it can replace HarappaWorld. I have sorted it into a Wikipedia table. A145029 (talk) 13:04, 5 May 2018 (UTC)Reply
Populations Ancestral North Indian (ANI) Ancestral South Indian (ASI) Ancestral Austroasiatic (AAA) Ancestral Tibeto-Burman (ATB) Andaman archipelago (A&N)
Gujaratis 1 76.2% 9.4% 13.8% 0.3% 0.2%
Gujaratis 2 80.7% 7.1% 8.5% 3.1% 0.5%

@A145029:, thanks for finding it. Feel free to add it and remove Harappa Ancestry Project. The International HapMap Project (HapMap) had collected 98 samples of Gujarati people living in Houston, Texas, United States which was processed by the HAP. Is this dataset useful in anyway? Should we mention it anywhere? If yes, feel free to do accordingly. And thank you for recent updates. Regards,--Nizil (talk) 18:06, 5 May 2018 (UTC)Reply

I have replaced HarappaWorld with the 2016 study. HarappaWorld may be somewhat useful but the categories are loosely defined and vague. The creator of the project himself said "I chose the names based on which populations in my data these components peaked in. They do not tell anything directly about ancestral populations."[2] Thus HarappaWorld is not really accurate and a study which uses scientifically defined terms like Ancestral North Indian is more reliable. Thanks for cooperation. A145029 (talk) 19:27, 5 May 2018 (UTC)Reply
Thank you. I have done some reorganisation in that section.--Nizil (talk) 05:47, 6 May 2018 (UTC)Reply
@Nizil Shah: In my opinion, it would be more useful to put the Autosomal DNA studies before the Autosomal DNA components, because the information from the studies provides more information about Gujaratis' genetics. Also, different studies provide slightly different estimates for ANI and ASI ancestry, thus a statement like "Gujaratis carry predominantly Ancestral North Indian genes" would be more useful and should be given more priority over the ANI and ASI estimates from a particular study. A145029 (talk) 18:01, 6 May 2018 (UTC)Reply
  1. ^ Sengupta, Dhriti; Choudhury, Ananyo; Basu, Analabha; Ramsay, Michèle (2016). "Population Stratification and Underrepresentation of Indian Subcontinent Genetic Diversity in the 1000 Genomes Project Dataset". Genome Biology and Evolution. 8 (11): 3460–3470. doi:10.1093/gbe/evw244. ISSN 1759-6653.
  2. ^ "HarappaWorld Admixture".