Talk:Somatic evolution in cancer

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Latest comment: 16 years ago1 comment1 person in discussion

The initial version of this page was written by members of the Santa Fe Institute working group on integrating evolutionary theory into cancer biology, including Carlo Maley, Brian Reid, John Pepper, Sabrina Spencer, Henry Heng and Tom Vincent.

There are some parts that could use some fleshing out:

Multilevel selection
Epigenetics
Phylogenetic analyses
Other forms of therapeutic resistance where the resistance has been caused by a known genetic or epigenetic (heritable) mechanism:
- Methotrexate
- Mutations and amplication of AR in anti-androgen therapy for prostate cancer
Add links to other wikipedia pages (e.g., Gefitinib? 5-flurouracil?)
Glossary

Carlo Maley (talk) 22:59, 16 July 2008 (UTC)Reply

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