Thermospermine synthase

Thermospermine synthase (EC 2.5.1.79, TSPMS, ACL5 (ACAULIS5), SAC51) is an enzyme with systematic name S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing).[1][2][3] This enzyme catalyses the following chemical reaction

Thermospermine synthase
Identifiers
EC no.2.5.1.79
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
S-adenosylmethioninamine + spermidine S-methyl-5'-thioadenosine + thermospermine + H+

This enzyme is required for correct xylem specification through regulation of the lifetime of the xylem elements.

References

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  1. ^ Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P (November 2008). "Investigations about N-aminopropyl transferases probably involved in biomineralization". Journal of Physiology and Pharmacology. 59 Suppl 5: 27–37. PMID 19075322.
  2. ^ Knott JM, Römer P, Sumper M (June 2007). "Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine". FEBS Letters. 581 (16): 3081–6. doi:10.1016/j.febslet.2007.05.074. PMID 17560575.
  3. ^ Muñiz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blázquez MA, Tuominen H (August 2008). "ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death". Development. 135 (15): 2573–82. doi:10.1242/dev.019349. PMID 18599510.
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