Urolithin B

Urolithin B
Names
	Preferred IUPAC name 3-Hydroxy-6H-dibenzo[b,d]pyran-6-one
	Other names Uro-B; 3-Hydroxyurolithin
Identifiers
CAS Number	1139-83-9 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1526978;
ChemSpider	4528673;
ECHA InfoCard	100.236.446
KEGG	C22596;
PubChem CID	5380406;
UNII	B1S2YM5F6G ;
CompTox Dashboard (EPA)	DTXSID00150610 ;
	InChI InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H Key: WXUQMTRHPNOXBV-UHFFFAOYSA-N;
	SMILES C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O;
Properties
Chemical formula	C13H8O3
Molar mass	212.204 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Urolithin B (UB)^[1] is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate,^[2] strawberries, red raspberries, walnuts or oak-aged red wine.^[3] Urolithin B is found in the urine in the form of urolithin B glucuronide. ^{[citation needed]}

References

^ Ghosh N, Das A, Biswas N, Gnyawali S, Singh K, Gorain M, Polcyn C, Khanna S, Roy S, Sen CK (19 November 2020). "Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1". Nature. 10 (1). Scientific Reports: 20184. doi:10.1038/s41598-020-76564-7. PMC 7678835. PMID 33214614.
^ Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 November 2009). "Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay". J Agric Food Chem. 57 (21): 10181–6. doi:10.1021/jf9025794. PMID 19824638.
^ Cerdá B, Tomás-Barberán FA, Espín JC (2005). "Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability". Journal of Agricultural and Food Chemistry. 53 (2): 227–235. doi:10.1021/jf049144d. PMID 15656654.

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Names

Preferred IUPAC name 3-Hydroxy-6H-dibenzo[b,d]pyran-6-one
Other names Uro-B 3-Hydroxyurolithin
Identifiers
CAS Number	1139-83-9^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1526978
ChemSpider	4528673
ECHA InfoCard	100.236.446
KEGG	C22596
PubChem CID	5380406
UNII	B1S2YM5F6G^Y
CompTox Dashboard (EPA)	DTXSID00150610
InChI InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H Key: WXUQMTRHPNOXBV-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
Properties
Chemical formula	C₁₃H₈O₃
Molar mass	212.204 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references