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Local hormones are a large group of signaling molecules that do not circulate within the blood.[1] Local hormones are produced by cells and bind to either neighboring cells or the same type of cell that produced them.
Eicosanoids (ī′kō-să-noydz; eicosa = twenty, eidos = formed) are a primary type of local hormone.[1] These local hormones are formed by a chain of 20 amino acids and fatty acids from phospholipids in the cell membrane.[1] Eicosanoids initiate either autocrine stimulation or paracrine stimulation.
Prostaglandins are the most diverse category of eicosanoids and are thought to be synthesized in most tissues of the body.[1] This type of local hormone stimulates pain receptors and increases the inflammatory response.[1] Nonsteroidal anti-inflammatory drugs stop the formation of prostaglandins, thus inhibiting these responses.
| This is a user sandbox of Goliath11. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |
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