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The organochlorine pentachlorophenol (PCP, C₆Cl₅OH) is a wood preservative biocide.

Structure

PCP is a polychlorinated aromatic:

Degradation

PCP is degraded by some bacteria, including Sphingobium chlorophenolicum^[1].

PCP → TCHQ → TriCHQ → DCHQ → 2,4-dichloro-3-hydroxy-cis,cis-muconic semialdehyde

NKG2D is related in no way whatsoever^[2].

References

^ Copley, Shelly D (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends in Biochemical Sciences. 25 (6): 261–265. doi:10.1016/S0968-0004(00)01562-0.
^ Farhadi, Nazanin; Lambert, Laura; Triulzi, Chiara; Openshaw, Peter J.M.; Guerra, Nadia; Culley, Fiona J. (March 2014). "Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation⋆". Journal of Allergy and Clinical Immunology. 133 (3): 827–835.e3. doi:10.1016/j.jaci.2013.09.048. {{cite journal}}: no-break space character in |title= at position 58 (help)

External links

US EPA: pentachlorophenol in drinking water

[Copley2000-1] Copley, Shelly D (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends in Biochemical Sciences. 25 (6): 261–265. doi:10.1016/S0968-0004(00)01562-0.

[2] Farhadi, Nazanin; Lambert, Laura; Triulzi, Chiara; Openshaw, Peter J.M.; Guerra, Nadia; Culley, Fiona J. (March 2014). "Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation⋆". Journal of Allergy and Clinical Immunology. 133 (3): 827–835.e3. doi:10.1016/j.jaci.2013.09.048. {{cite journal}}: no-break space character in |title= at position 58 (help)

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