1921

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New Mexico
(Class 2)
Holm O. Bursum Republican 1921 (appointed) Interim appointee elected September 20, 1921.
  •  Y Holm O. Bursum (Republican) 51.4%
  • Richard H. Hanna (Democratic) 43.7%
  • A. A. Sena (Independent) 4.0%
  • T. S. Smith (Socialist) 0.9%

1925

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Wisconsin
(Class 1)
Robert M. La Follette Republican 1905
1911
1916
1922
Incumbent died June 18, 1925.
New senator elected September 29, 1925.
Republican hold.

1931

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Vermont
(Class 1)
Frank C. Partridge Republican 1930 (appointed) Interim appointee lost nomination.
New senator elected March 31, 1931.
Republican hold.
  •  Y Warren Austin (Republican) 64.0%
  • Stephen M. Driscoll (Democratic) 35.6%

1933

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Virginia
(Class 1)
Harry F. Byrd Democratic 1933 (appointed) Interim appointee elected November 7, 1933.
  •  Y Harry F. Byrd (Democratic) 71.3%
  • Henry A. Wise (Republican) 26.7%
Others
  • John M. Daniel (Independent) 0.9%
  • Elizabeth L. Otey (Socialist) 0.7%
  • Hewman H. Raymond (Prohibition) 0.4%

1937

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Arkansas
(Class 2)
Joseph T. Robinson Democratic 1913
1918
1924
1930
1936
Incumbent died July 14, 1937.
New senator elected October 19, 1937.
Democratic hold.

1947

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Mississippi
(Class 1)
Theodore G. Bilbo Democratic 1934
1940
1946
Incumbent died August 21, 1947.
New senator elected November 4, 1947.
Democratic hold.

1949

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New York
(Class 3)
John Foster Dulles Republican 1949 (appointed) Interim appointee lost election.
New senator elected November 8, 1949.
Democratic gain.

1961

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Texas
(Class 2)
William A. Blakley Democratic 1961 (appointed) Interim appointee lost election.
New senator elected May 27, 1961.
Republican gain.

1975

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New Hampshire
(Class 3)
Norris Cotton Republican 1954 (special)
1956
1962
1968
1974 (retired)
1975 (appointed)
Interim appointee retired.
New senator elected September 16, 1975.
Democratic gain.

1983

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Washington
(Class 1)
Daniel J. Evans Republican 1983 (appointed) Interim appointee elected November 8, 1983.

1991

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Pennsylvania
(Class 1)
Harris Wofford Democratic 1991 (appointed) Interim appointee elected November 5, 1991.

1993

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Texas
(Class 1)
Bob Krueger Democratic 1993 (appointed) Interim appointee lost election.
New senator elected June 6, 1993.
Republican gain.

2017

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Alabama
(Class 2)
Luther Strange Republican 2017 (appointed) Interim appointee lost nomination.
New senator elected December 12, 2017.
Democratic gain.