The organochlorine pentachlorophenol (PCP, C6Cl5OH) is a wood preservative biocide.

Structure

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PCP is a polychlorinated aromatic:

 

Degradation

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PCP is degraded by some bacteria, including Sphingobium chlorophenolicum [1]

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reuse ref [1]


PCP → TCHQ → TriCHQ → DCHQ → 2,4-dichloro-3-hydroxy-'cis, cis-muconic semialdehyde

References

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  1. ^ a b Copley, S (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends in Biochemical Science. 25(6): 261–265. doi:10.1016/S0968-0004(00)01562-0.
  2. ^ Parikh, Kaushal; Antanaviciute, Agne; Fawkner-Corbett, David; Jagielowicz, Marta; Aulicino, Anna; Lagerholm, Christoffer; Davis, Simon; Kinchen, James; Chen, Hannah H.; Alham, Nasullah Khalid; Ashley, Neil; Johnson, Errin; Hublitz, Philip; Bao, Leyuan; Lukomska, Joanna; Andev, Rajinder Singh; Björklund, Elisabet; Kessler, Benedikt M.; Fischer, Roman; Goldin, Robert; Koohy, Hashem; Simmons, Alison (27 February 2019). "Colonic epithelial cell diversity in health and inflammatory bowel disease". Nature. doi:10.1038/s41586-019-0992-y.


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