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— Wikipedian ♂ — | |
Name | Uttam Pal |
---|---|
Born | |
Current location | Kolkata, India |
Contact info | |
Website | uttampal |
Welcome!
editI am a researcher at Satyendra Nath Bose National Centre for Basic Sciences, Kolkata. My area of interest is computational chemistry. I study atomistic and electronic structure models of small molecules, materials and chemical reactions using quantum or classical mechanics. I also study biomolecules such as proteins and nucleic acids, and their interactions with small molecules. How the drug molecules work, why they cease to work and how we can develop new drugs are the areas I explore through my research.
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Alma mater
editI attended Presidency College, Kolkata of the University of Calcutta for my undergraduate studies and I have earned a bachelor's degree with honours in physiology from there in 2008. Then I went to the University College of Science, Technology and Agriculture of the University of Calcutta and completed my master's degree in biophysics & molecular biology in 2010. After that, I joined the doctoral research programme of the CSIR - Indian Institute of Chemical Biology (IICB) under INSPIRE Fellowship programme of Department of Science and Technology (India) in 2011. Got registered as a doctoral student in the Department of Chemistry of Jadavpur University. Defended my thesis there in the August of 2016.
Scientific associations
edit- Member of the Royal Society of Chemistry (RSC) since 2017
- Member of the American Association for the Advancement of Science (AAAS) since 2012
- Member of the American Chemical Society (ACS) since 2014
- Life member of the Indian Biophysical Society, Indian Science Congress Association, National Magnetic Resonance Society (India), The Society of Biological Chemists (India)
- Editorial Board member of the Applied Biochemistry and Biotechnology, Frontiers in Chemistry and Frontiers in Public Health
- Reviewer of the several journals including RSC Advances, ACS Omega etc.
My research works
editFull text of the published research articles are available from my ResearchGate profile.
- Binding of Hemoglobin to Ultrafine Carbon Nanoparticles: A Spectroscopic Insight into a Major Health Hazard.[1] RSC Advances.
- Sequence complexity of amyloidogenic regions in intrinsically disordered human proteins.[2] PLOS ONE.
- Cα–H carries information of a hydrogen bond involving the geminal hydroxyl group: A case study with a hydrogen-bonded complex of 1,1,1,3,3,3-hexafluoro-2-propanol and tertiary amines.[3] The Journal of Physical Chemistry A.
- pKa determination of D-ribose by Raman spectroscopy.[4] The Journal of Physical Chemistry B.
- Stereoselective domino azidation and [3 + 2] cycloaddition: a facile route to chiral heterocyclic scaffolds from carbohydrate derived synthons.[5] RSC Advances.
- Chaperone action of cyclophilin on lysozyme and its aggregate.[6] Journal of Proteins and Proteomics.
- Copper(I) oxide nanoparticle and tryptophan as its biological conjugate: a modulation of cytotoxic effects.[7] Journal of Nanoparticle Research.
- Potent anticancer activity of cystine-based dipeptides and their interaction with serum albumins.[8] Chemistry Central Journal.
- Dipeptide derived from benzylcystine forms unbranched nanotubes in aqueous solution.[9] Journal of Nanostructure in Chemistry.
- 2,2'-diphenyl-3,3'-diindolylmethane: A potent compound induces apoptosis in breast cancer cells by inhibiting EGFR pathway.[10] PLOS ONE.
- Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site.[11] Journal of Pineal Research.
- Conformation and cytotoxicity of a tetrapeptide constellated with alternative D- and L-proline.[12] RSC Advances.
- Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor.[13] Journal of Biological Chemistry.
- Interaction of Merocyanine 540 with serum albumins: photophysical and binding studies.[14] Journal of Photochemistry and Photobiology B: Biology.
- Nickel(II)-Schiff base complex recognizing domain II of bovine and human serum albumin: spectroscopic and docking studies.[15] Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.
- Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent.[16] Bioorganic & Medicinal Chemistry.
My editorial works
editI have edited and published two issues of the little magazine, Reminiscence. It is a bilingual magazine and includes the articles in English and বাংলা languages. The electronic versions are freely available online. Reminiscence, Issue I & II can be read at Issuu by following the links given below:
Other compilations
editI have compiled and published two ebooks authored by Nobel laureate Rabindranath Tagore. One is Gitanjali (Song Offerings), a collection of poems rendered into English by the poet himself, for which he was given the Nobel Prize in Literature in 1913. The other one is a philosophical work by Tagore, Sadhana: The Realization of Life, a compilation of lectures given to the Harvard students in 1913. These ebooks are freely available online.
Links to my online profiles
editReferences
edit- ^ Banerji, B.; Pramanik, S. K.; Pal, U.; Maiti, N. C. (2014). "Binding of hemoglobin to ultrafine carbon nanoparticles: A spectroscopic insight into a major health hazard". RSC Advances. 4 (43): 22536. doi:10.1039/C4RA02569E.
- ^ "Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins". PLoS ONE. 9 (3): e89781. 3 March 2014. doi:10.1371/journal.pone.0089781.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ "Cα–H Carries Information of a Hydrogen Bond Involving the Geminal Hydroxyl Group: A Case Study with a Hydrogen-Bonded Complex of 1,1,1,3,3,3-Hexafluoro-2-propanol and Tertiary Amines". The Journal of Physical Chemistry A. 118 (6): 1024–1030. 13 February 2014. doi:10.1021/jp411488a.
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ignored (help) - ^ "pKa Determination of D-Ribose by Raman Spectroscopy". The Journal of Physical Chemistry B. 118 (4): 909–914. 30 January 2014. doi:10.1021/jp4092392.
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ignored (help) - ^ "Stereoselective domino azidation and [3 + 2] cycloaddition: a facile route to chiral heterocyclic scaffolds from carbohydrate derived synthons". RSC Advances. 4 (8): 4155. 20 December 2013. doi:10.1039/C3RA45363D.
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ignored (help) - ^ "Chaperone action of cyclophilin on lysozyme and its aggregate". Journal of Proteins and Proteomics. 4 (2): 129. 14 December 2013.
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ignored (help) - ^ "Copper(I) oxide nanoparticle and tryptophan as its biological conjugate: a modulation of cytotoxic effects". Journal of Nanoparticle Research. 16 (1): 2179. December 2013. doi:10.1007/s11051-013-2179-z.
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ignored (help) - ^ "Potent anticancer activity of cystine-based dipeptides and their interaction with serum albumins". Chemistry Central Journal. 7 (1): 91. 1 January 2013. doi:10.1186/1752-153X-7-91.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ "Dipeptide derived from benzylcystine forms unbranched nanotubes in aqueous solution". Journal of Nanostructure in Chemistry. 3 (1): 12. 1 January 2013. doi:10.1186/2193-8865-3-12.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ "2,2′-Diphenyl-3,3′-Diindolylmethane: A Potent Compound Induces Apoptosis in Breast Cancer Cells by Inhibiting EGFR Pathway". PLoS ONE. 8 (3): e59798. 28 March 2013. doi:10.1371/journal.pone.0059798. PMID 23555785.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ "Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site". Journal of pineal research. 27 December 2012. doi:10.1111/jpi.12034. PMID 23330737.
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ignored (help) - ^ "Conformation and cytotoxicity of a tetrapeptide constellated with alternative d- and l-proline". RSC Advances. 2 (17): 6744. 1 January 2012. doi:10.1039/C2RA20616A.
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ignored (help) - ^ "Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor". The Journal of biological chemistry. 287 (29): 24844–61. 13 July 2012. doi:10.1074/jbc.M112.341321. PMID 22645149.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ "Interaction of Merocyanine 540 with serum albumins: photophysical and binding studies". Journal of photochemistry and photobiology. B, Biology. 108: 23–33. 1 March 2012. doi:10.1016/j.jphotobiol.2011.12.005. PMID 22264940.
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ignored (help) - ^ "Nickel(II)-Schiff base complex recognizing domain II of bovine and human serum albumin: spectroscopic and docking studies". Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 92: 164–74. 15 June 2012. doi:10.1016/j.saa.2012.02.060. PMID 22446763.
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ignored (help) - ^ "Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent". Bioorganic & medicinal chemistry. 19 (24): 7365–73. 15 December 2011. doi:10.1016/j.bmc.2011.10.056. PMID 22088307.
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External links
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