Vestigial like family member 4 is a protein that in humans is encoded by the VGLL4 gene .
[ 5]
Chen HH, Mullett SJ, Stewart AF (July 2004). "Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes" . J. Biol. Chem . 279 (29): 30800–6. doi :10.1074/jbc.M400154200 PMID 15140898 . Chen HH, Mullett SJ, Stewart AF (July 2004). "Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes" . J. Biol. Chem . 279 (29): 30800–6. doi :10.1074/jbc.M400154200 PMID 15140898 . Chen HH, Mullett SJ, Stewart AF (July 2004). "Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes" . J. Biol. Chem . 279 (29): 30800–6. doi :10.1074/jbc.M400154200 PMID 15140898 . Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (August 2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling" . Gut . 58 (8): 1078–83. doi :10.1136/gut.2008.169052 . PMID 19240061 . S2CID 17111427 . Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score" . Mol. Med . 16 (7–8): 247–53. doi :10.2119/molmed.2009.00159 . PMC 2896464 PMID 20379614 . Teng AC, Kuraitis D, Deeke SA, Ahmadi A, Dugan SG, Cheng BL, Crowson MG, Burgon PG, Suuronen EJ, Chen HH, Stewart AF (December 2010). "IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression" . FASEB J . 24 (12): 4825–34. doi :10.1096/fj.10-167049 PMID 20702774 . S2CID 35708173 . Jin HS, Park HS, Shin JH, Kim DH, Jun SH, Lee CJ, Lee TH (September 2011). "A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration". Biochem. Biophys. Res. Commun . 412 (3): 454–9. doi :10.1016/j.bbrc.2011.07.117 . PMID 21839727 . Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA (December 2013). "Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells" . Stem Cells . 31 (12): 2833–41. doi :10.1002/stem.1445 . PMC 4617635 PMID 23765749 . Zhang W, Gao Y, Li P, Shi Z, Guo T, Li F, Han X, Feng Y, Zheng C, Wang Z, Li F, Chen H, Zhou Z, Zhang L, Ji H (March 2014). "VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex" . Cell Res . 24 (3): 331–43. doi :10.1038/cr.2014.10 . PMC 3945886 PMID 24458094 .
