ZMYND10

Zinc finger MYND domain-containing protein 10 is a protein that in humans is encoded by the ZMYND10 gene.

ZMYND10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D8Q, 2DAN
Identifiers
Aliases	ZMYND10, BLU, CILD22, FLU, zinc finger MYND-type containing 10, DNAAF7
External IDs	OMIM: 607070; MGI: 2387863; HomoloGene: 9293; GeneCards: ZMYND10; OMA:ZMYND10 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3p21.31 Start 50,341,110 bp End 50,345,732 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 F1 Start 107,424,497 bp End 107,428,518 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube left testis right testis bronchial epithelial cell olfactory zone of nasal mucosa testicle mucosa of paranasal sinus right lung gonad nasal epithelium Top expressed in spermatocyte seminiferous tubule morula spermatid right kidney proximal tubule human kidney olfactory epithelium Epithelium of choroid plexus secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding Cellular component cytoplasm centriolar satellite cytoskeleton microtubule organizing center apical plasma membrane plasma membrane membrane Biological process outer dynein arm assembly motile cilium assembly inner dynein arm assembly positive regulation of motile cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51364 114602 Ensembl ENSG00000004838 ENSMUSG00000010044 UniProt O75800 Q99ML0 RefSeq (mRNA) NM_001308379 NM_015896 NM_053253 NM_001379079 NM_001379080 RefSeq (protein) NP_001295308 NP_056980 NP_444483 NP_001366008 NP_001366009 NP_001391876 Location (UCSC) Chr 3: 50.34 – 50.35 Mb Chr 9: 107.42 – 107.43 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Lerman MI, Minna JD (2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium". Cancer Res. 60 (21): 6116–33. PMID 11085536.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liu XQ, Chen HK, Zhang XS, et al. (2003). "Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma". Int. J. Cancer. 106 (1): 60–5. doi:10.1002/ijc.11166. PMID 12794757. S2CID 22730979.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Qiu GH, Tan LK, Loh KS, et al. (2004). "The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma". Oncogene. 23 (27): 4793–806. doi:10.1038/sj.onc.1207632. PMID 15122337. S2CID 20374420.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Marsit CJ, Kim DH, Liu M, et al. (2005). "Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence". Int. J. Cancer. 114 (2): 219–23. doi:10.1002/ijc.20714. PMID 15540210. S2CID 6691671.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode:2006Natur.440.1194M. doi:10.1038/nature04728. PMID 16641997.