The Hepatitis B virus PRE stem-loop beta (HBV PRE SL-beta) is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs.
| Hepatitis B virus PRE beta | |
|---|---|
| Identifiers | |
| Symbol | HBV_PREbeta |
| Rfam | HBV_PREbeta |
| Other data | |
| RNA type | Cis-reg; |
| PDB structures | PDBe |
The minimal HBV PREbeta structure consists of a 23 nt stem-loop, with a 9 nt apical loop. The conserved stem-loop was predicted within the HBV PRE sequence and confirmed by mutagenesis.[1][2]
See also
editReferences
edit- ^ Smith Gj, 3rd; Donello, JE; Lück, R; Steger, G; Hope, TJ (1998). "The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function". Nucleic Acids Research. 26 (21): 4818–4827. doi:10.1093/nar/26.21.4818. PMC 147918. PMID 9776740.
{{cite journal}}: CS1 maint: numeric names: authors list (link) - ^ Chen, A; Panjaworayan T-Thienprasert, N; Brown, CM (7 July 2014). "Prospects for inhibiting the post-transcriptional regulation of gene expression in hepatitis B virus". World Journal of Gastroenterology. 20 (25): 7993–8004. doi:10.3748/wjg.v20.i25.7993. PMC 4081668. PMID 25009369.
 | This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |