The Mnt internal ribosome entry site (IRES) is an RNA element. Mnt is a transcriptional repressor related to the Myc/Mad family of transcription factors. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.[1]
| Mnt IRES | |
|---|---|
 Predicted secondary structure and sequence conservation of IRES_mnt | |
| Identifiers | |
| Symbol | IRES_mnt |
| Rfam | RF00457 |
| Other data | |
| RNA type | Cis-reg; IRES |
| Domain(s) | Eukaryota |
| GO | GO:0043022 |
| SO | SO:0000243 |
| PDB structures | PDBe |
See also
editReferences
edit- ^ Stoneley M, Spencer JP, Wright SC (February 2001). "An internal ribosome entry segment in the 5' untranslated region of the mnt gene". Oncogene. 20 (7): 893–897. doi:10.1038/sj.onc.1204157. PMID 11314024.
External links
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