| Issue Date | Song | Artist(s) |
|---|---|---|
| January 2 | "I Feel Fine" | The Beatles |
| January 9 | ||
| January 16 | ||
| January 23 | ||
| January 30 | "Oh, Pretty Woman" | Roy Orbison |
| February 6 | ||
| February 13 | ||
| February 20 | ||
| February 27 | ||
| March 6 | ||
| March 13 | "Downtown" | Petula Clark |
| March 20 | ||
| March 27 | ||
| April 3 | ||
| April 10 | "You've Lost That Lovin' Feelin'" | The Righteous Brothers |
| April 17 | ||
| April 24 | ||
| May 1 | "Eight Days a Week" | The Beatles |
| May 8 | ||
| May 15 | ||
| May 22 | ||
| May 29 | ||
| June 5 | "Ticket to Ride" | |
| June 12 | ||
| June 19 | ||
| June 26 | ||
| July 3 | ||
| July 10 | ||
| July 17 | "It's Not Unusual" | Tom Jones |
| July 24 | ||
| July 31 | ||
| August 7 | "Mr. Tambourine Man" | The Byrds |
| August 14 | ||
| August 21 | ||
| August 28 | ||
| September 4 | "(I Can't Get No) Satisfaction" † | The Rolling Stones |
| September 11 | ||
| September 18 | ||
| September 25 | ||
| October 2 | ||
| October 9 | ||
| October 16 | ||
| October 23 | ||
| October 30 | ||
| November 6 | "I Got You Babe" | Sonny & Cher |
| November 13 | ||
| November 20 | ||
| November 27 | ||
| December 4 | ||
| December 11 | "Yesterday" | The Beatles |
| December 18 | ||
| December 25 |
