Wikipedia

PrasannR

Joined 13 April 2017

Final Presentation about Cardiac Glycosides

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https://docs.google.com/presentation/d/19ldMs3f7TwWAenF2FNQwjqjwhlvtaSQ1RuxhitIONRQ/edit?usp=sharing

Peer Review Comments for Me

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Juka Kim:

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First of all I really like what you did to your userpage! It's really organized and neat.

- I think Cardenolides and bufadienolides in "Cardenolides differ from bufadienolides" can be linked to its own Wikipedia pages.

- "Most directly, cardiac glycosides affect...cells to alter its function." : I think "most directly" sounds a little awkward for substituting it with a different word may be a good idea.

- "Normally, these sodium-potassium pumps pump potassium ions in and sodium ions out." : I think "pumps pump" is kind of redundant here

- "This effect leads initially to bigeminy: regular ectopic beats following each ventricular contraction." : maybe link "bigeminy" here if the word is defined on Wikipedia

- "Additionally, these compounds have been implicated in cell growth and signaling pathways and have been suggested to be classified as steroid hormones in their own right" : I think "in their own right" is unnecessary here

Overall, I think you have already made a great contribution and it looks like you are really comfortable with Wikipedia. I found the plant fact interesting. The links to other wikipedia pages are used efficiently and appropriately. I don't know how to tell if you added a picture or not but if you haven't already it might be worth while to add one because you go in depth about the structure.

Brittney Nchako:

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- See separate paper

Final Article Choice: Cardiac Glycoside

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Peer-Review Article Choices: Interleukin-8 Receptor and Photo-Induced Crosslinking (check User:Jukakim/sandbox)

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Reference List

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[1][2][3][4][5]

  1. ^ Patel, Seema (2016-12-01). "Plant-derived cardiac glycosides: Role in heart ailments and cancer management". Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 84: 1036–1041. doi:10.1016/j.biopha.2016.10.030. ISSN 1950-6007. PMID 27780131.
  2. ^ Ambrosy, Andrew P.; Butler, Javed; Ahmed, Ali; Vaduganathan, Muthiah; van Veldhuisen, Dirk J.; Colucci, Wilson S.; Gheorghiade, Mihai (2014-05-13). "The use of digoxin in patients with worsening chronic heart failure: reconsidering an old drug to reduce hospital admissions". Journal of the American College of Cardiology. 63 (18): 1823–1832. doi:10.1016/j.jacc.2014.01.051. ISSN 1558-3597. PMID 24613328.
  3. ^ Riganti, C.; Campia, I.; Kopecka, J.; Gazzano, E.; Doublier, S.; Aldieri, E.; Bosia, A.; Ghigo, D. (2011-01-01). "Pleiotropic effects of cardioactive glycosides". Current Medicinal Chemistry. 18 (6): 872–885. ISSN 1875-533X. PMID 21182478.
  4. ^ Babula, Petr; Masarik, Michal; Adam, Vojtech; Provaznik, Ivo; Kizek, Rene (2013-09-01). "From Na+/K+-ATPase and cardiac glycosides to cytotoxicity and cancer treatment". Anti-Cancer Agents in Medicinal Chemistry. 13 (7): 1069–1087. ISSN 1875-5992. PMID 23537048.
  5. ^ Somogyi, János; Szalay, Júlia; Pándics, Tamás; Rosta, Klára; Csermely, Péter; Vér, Agota (2004-02-08). "[New steroid hormone family: endogenous cardiac glycosides and their role in physiologic and pathologic conditions]". Orvosi Hetilap. 145 (6): 259–266. ISSN 0030-6002. PMID 15038319.

Added introduction paragraph to Cardiac Glycoside

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"Cardiac glycosides are a class of organic compounds that affect the inotropic and chronotropic activity of the heart by acting on the sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for congestive heart failure and cardiac arrhythmias. Nevertheless, they have a diverse range of biochemical effects regarding cell growth and development and have also been suggested for use in cancer treatment." PrasannR (talk) 21:42, 4 May 2017 (UTC)

Other article candidates

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Class Notes

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6/8 Class Notes:

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TO-DO: Submit final article pdf + submit reflective essay by 6/16

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6/1 Class Notes:

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  • First draft information: Focus on reducing technical language so make sure to define all terms such that high-school students can understand them
    • Basically add in a few words/phrase to briefly define the term before using it
  • Next week: Five-minute oral presentation of topic, can use ppt/prezi, have it be internet-accessible
    • Basically share with classmates whatever content I added to my article

TO-DO: Prepare 5 minute oral presentation by 6/8

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5/25 Class Notes:

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  • Feedback for first drafts will be received by 6/1
  • In-class presentation on 6/8
    • 5 minute presentation on basically on what I added to the cardiac glycoside page+any necessary background
  • Final draft due finals week!
  • Peer Review focus: Tone, Bias, Relevance, Accuracy, Organization, Possible additional information, Clarity, Depth of topic, Grammar
    • Basically whatever I would like others to say on my page, I should say for others'
    • Can also photocopy peer reviews for peer+Professor

TO-DO: Post peer reviews for articles on user page by 6/1

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5/18 Class Notes:

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  • Print out full article for class next week with what I added highlighted (alternately, with what I did not add highlighted if I end up adding a lot)
  • Final article in Word should be about 1-2 pages of text (single-spaced)
  • Everything should be properly cited (with in-text references)
    • Use about 50:50 primary:secondary sources
    • For medically relevant articles, should cite reviews that are 1-5 years old
  • Media Literacy: recognizing fake news, evaluating articles for bias, looking for what's missing/isn't being shown,

TO-DO: First draft due 5/25!

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5/11 Class Notes:

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  • For images, make sure to only use public domain free license copyright images
  • Add images by insert--media, can change settings of image with Edit mode
  • Can also upload an image I make of a compound using Pymol and then add it into the article
  • If you do a Google search for an image, the default is to assume that the image is copyright unless you know it is public domain/free license
    • This means that you can cite textbooks but cannot use their images (need to change substantial information and make it your own)
    • If make image from Pymol, just include PDB code for reference

TO-DO: Keep progressing on outline for proposed edits to my article (First draft due 5/25! outline will become live edits)

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5/4 Class Notes:

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  • May 25: First draft due, so outline will now become live edits on article
    • Also bring hard copies of these to class (mark what I changed) so that Prof. +2 peers can review them-->peers will give feedback on my own page

TO-DO: Summarize what changes you want to make to page on article's talk page and request for feedback from other users about posted outline

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  • Post outline of suggested changes to talk page, 1-3 sentences on what each section would include is pretty good

4/27 Class Notes:

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  • Generally use secondary sources like textbooks/review articles and some primary literature
  • Helpful reference pages: "WP:REFB" & "WP:CITE"

TO-DO Initial Bibliography with 5 articles + Make first edit to live wikipedia page

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4/20 Class Notes:

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  • Consider reading choosing articles guideline on website.
  • Generally will be start/stub class article.
  • Try multiple different names for the topic, should prolly be something you're interested in in biochem (any protein/metabolite/process)
  • Balance interest in the topic with usefulness in the course to maximize efficiency.
  • Refrain from really broad topics because the longer the article the less room to expand it
  • Stay away from controversial
  • Be careful about directly medically relevant article because your article shouldn't be used for medical advice
  • Wikipedia:WikiProject Molecular and Cell Biology tagged topics about relevance to MCDB
    • Stub: title+sentence//Start: paragraph//C: barest vestige of an article//B: getting there, on the way//GA: good article//FA: featured article
    • also wiki project on women scientists
  • Wikipedia:WikiProject Women scientists
  • Category:Biochemistry
  • former article suggestions: enzyme catalysis, active site, brown adipose tissue, proton wires, any complex in ETC, any enzyme/metabolite in glycolysis (most C class articles), taste receptors

TO-DO: Edit user page to add 3-5 articles to edit.

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Brainstorming articles:

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