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| Virus | SARS-CoV-2[a] | MERS-CoV | SARS-CoV | H1N1, H3N2 |
|---|---|---|---|---|
| Disease | COVID-19 | Middle East respiratory syndrome | Severe acute respiratory syndrome | Seasonal flu |
| Epidemiology | ||||
| Detection date | December 2019 | June 2012 | November 2002 | Endemic (n.a.) |
| Detection place | Wuhan, China | Jeddah, Saudi Arabia | Guangdong, China | Endemic (n.a.) |
| Confirmed cases | 88,585[b] | 2494 | 8096 | 5~15,000,000/y |
| Case fatality rate | 3,043[b] (3.44%) | 858 (37%) | 744 (10%) | 290-650,000 (0.1%) |
| Basic reproduction number | 2.2 (95% CI:1.4–3.9)[2][3]
2.68 (95% CI:2.47–2.86)[4] |
1.3 | ||
| Serial interval period | 7.5±3.4 days (95% CI:5.3–19)[2] | |||
| Demographic | ||||
| Age average | 49 | 56 | 39.9 | |
| Age range | 21–76 | 14–94 | 1–91 | |
| Male:female ratio | 2.7:1 | 3.3:1 | 1:1.25 | |
| Health-care workers | 16[c] | 9.8% | 23.1% | |
| Symptoms | ||||
| Fever | 40 (98%) | 98% | 99–100% | |
| Dry cough | 31 (76%) | 47% | 29–75% | |
| Dyspnea/short breath | 22 (55%) | 72% | 40–42% | |
| Diarrhea | 1 (3%) | 26% | 20–25% | |
| Sore throat | 0 | 21% | 13–25% | |
| Ventilatory support | 9.8% | 80% | 14–20% | |
| Prognostic/Evolution | ||||
| Incubation | 5.5 days (1–14)[5][6] or
5.2 days (95% CI:4.1–7.0)[2] |
2-4 days | ||
| Onset | Day 0 | Day 0 | ||
| First medical visit | +4.6 days (95% CI:4.1–5.1)[2] | |||
| Hospital admission | +7.0 days (4.0–8.0)[7] or | |||
| Dyspnea/short breath | +8.0 days (5.0–13.0)[7] | |||
| ARDS | +9.0 days (8.0–14.0)[7] | |||
| Mechanical ventilation / ICU | +10.5 days (7.0–14.0)[7] | |||
| Recovery | +22.2 days (95% CI:18–83)[8] | |||
| Dead | +14 days (6–41)[9] or
hospitalization + 12.4[10] +22.3 days (95% CI:18–82)[8] |
|||
| Notes | ||||
See also
edit- parameter_estimates/2019_novel_coronavirus
- [1]
- Update symptoms : use this.
References
- ^ Wang, Chen; Horby, Peter W.; Hayden, Frederick G.; Gao, George F. (24 January 2020). "A novel outbreak of global health concern". The Lancet. 395 (10223): 470–473. doi:10.1016/S0140-6736(20)30185-9. PMC 7135038. PMID 31986257.
- ^ a b c d e f Li, Qun; Guan, Xuhua; Wu, Peng; Wang, Xiaoye; Zhou, Lei; Tong, Yeqing; Ren, Ruiqi; Leung, Kathy S.M.; Lau, Eric H.Y.; Wong, Jessica Y.; Xing, Xuesen (2020-01-29). "Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia". New England Journal of Medicine. 382 (13): 1199–1207. doi:10.1056/NEJMoa2001316. ISSN 0028-4793. PMC 7121484. PMID 31995857.
- ^ a b c Fauci, Anthony S.; Lane, H. Clifford; Redfield, Robert R. (2020-02-28). "Covid-19 — Navigating the Uncharted". New England Journal of Medicine. 382 (13): 1268–1269. doi:10.1056/NEJMe2002387. ISSN 0028-4793. PMC 7121221. PMID 32109011.
- ^ Wu, Joseph T.; Leung, Kathy; Leung, Gabriel M. (2020-02-29). "Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study". The Lancet. 395 (10225): 689–697. doi:10.1016/S0140-6736(20)30260-9. ISSN 0140-6736. PMC 7159271. PMID 32014114.
- ^ "Q&A on coronaviruses (COVID-19) : How long is the incubation period for COVID-19?". www.who.int. Retrieved 2020-03-02.
- ^ "Coronavirus disease 2019 (COVID-19) Situation Report – 29" (PDF). World Health Organization. 2020-02-19.
- ^ a b c d Ronco, Claudio; Navalesi, Paolo; Vincent, Jean Louis (2020-02-06). "Coronavirus epidemic: preparing for extracorporeal organ support in intensive care". The Lancet Respiratory Medicine. 8 (3): 240–241. doi:10.1016/S2213-2600(20)30060-6. ISSN 2213-2600. PMC 7154507. PMID 32035509.
- ^ a b "Report 4: Severity of 2019-novel coronavirus (nCoV)" (PDF). WHO Collaborating Centre for Infectious Disease Modelling MRC Centre for Global Infectious Disease Analysis. 2020-02-10.
- ^ W, Wang; J, Tang; F, Wei (April 2020). "Updated Understanding of the Outbreak of 2019 Novel Coronavirus (2019-nCoV) in Wuhan, China". Journal of Medical Virology. 92 (4): 441–447. doi:10.1002/jmv.25689. PMC 7167192. PMID 31994742.
- ^ Famulare, Mike (2020-02-19). "2019-nCoV: preliminary estimates of the confirmed-case-fatality-ratio and infection-fatality-ratio, and initial pandemic risk assessment". institutefordiseasemodeling.github.io. Retrieved 2020-03-02.