- INFO: Beginning work on ADMR... {November 25, 2007 9:19:36 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:20:24 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Adrenomedullin receptor
| HGNCid = 13708
| Symbol = ADMR
| AltSymbols =; 7TMR; AMR; MGC34399; gamrh; hrhAMR
| OMIM = 605307
| ECnumber =
| Homologene = 5255
| MGIid = 109545
| GeneAtlas_image1 = PBB_GE_ADMR_214506_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 11318
| Hs_Ensembl = ENSG00000166856
| Hs_RefseqProtein = NP_009195
| Hs_RefseqmRNA = NM_007264
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 12
| Hs_GenLoc_start = 55674497
| Hs_GenLoc_end = 55676735
| Hs_Uniprot = O15218
| Mm_EntrezGene = 11536
| Mm_Ensembl =
| Mm_RefseqmRNA = NM_007412
| Mm_RefseqProtein = NP_031438
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Adrenomedullin receptor''', also known as '''ADMR''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ADMR adrenomedullin receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11318| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin.<ref name="entrez">{{cite web | title = Entrez Gene: ADMR adrenomedullin receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11318| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Lah JJ, Frishman WH |title=Adrenomedullin: a vasoactive and natriuretic peptide with therapeutic potential. |journal=Heart disease (Hagerstown, Md.) |volume=2 |issue= 3 |pages= 259-65 |year= 2002 |pmid= 11728267 |doi= }}
*{{cite journal | author=Mukoyama M, Sugawara A, Nagae T, ''et al.'' |title=Role of adrenomedullin and its receptor system in renal pathophysiology. |journal=Peptides |volume=22 |issue= 11 |pages= 1925-31 |year= 2002 |pmid= 11754983 |doi= }}
*{{cite journal | author=Fowler DE, Wang P |title=The cardiovascular response in sepsis: proposed mechanisms of the beneficial effect of adrenomedullin and its binding protein (review). |journal=Int. J. Mol. Med. |volume=9 |issue= 5 |pages= 443-9 |year= 2002 |pmid= 11956648 |doi= }}
*{{cite journal | author=Kato J, Kitamura K, Kangawa K, Eto T |title=Receptors for adrenomedullin in human vascular endothelial cells. |journal=Eur. J. Pharmacol. |volume=289 |issue= 2 |pages= 383-5 |year= 1995 |pmid= 7621913 |doi= }}
*{{cite journal | author=MartÃnez A, Miller MJ, Catt KJ, Cuttitta F |title=Adrenomedullin receptor expression in human lung and in pulmonary tumors. |journal=J. Histochem. Cytochem. |volume=45 |issue= 2 |pages= 159-64 |year= 1997 |pmid= 9016306 |doi= }}
*{{cite journal | author=Hänze J, Dittrich K, Dötsch J, Rascher W |title=Molecular cloning of a novel human receptor gene with homology to the rat adrenomedullin receptor and high expression in heart and immune system. |journal=Biochem. Biophys. Res. Commun. |volume=240 |issue= 1 |pages= 183-8 |year= 1997 |pmid= 9367907 |doi= 10.1006/bbrc.1997.7631 }}
*{{cite journal | author=MartÃnez A, Elsasser TH, Muro-Cacho C, ''et al.'' |title=Expression of adrenomedullin and its receptor in normal and malignant human skin: a potential pluripotent role in the integument. |journal=Endocrinology |volume=138 |issue= 12 |pages= 5597-604 |year= 1997 |pmid= 9389548 |doi= }}
*{{cite journal | author=Kennedy SP, Sun D, Oleynek JJ, ''et al.'' |title=Expression of the rat adrenomedullin receptor or a putative human adrenomedullin receptor does not correlate with adrenomedullin binding or functional response. |journal=Biochem. Biophys. Res. Commun. |volume=244 |issue= 3 |pages= 832-7 |year= 1998 |pmid= 9535752 |doi= 10.1006/bbrc.1998.8349 }}
*{{cite journal | author=Jiménez N, Calvo A, MartÃnez A, ''et al.'' |title=Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in human and rat prostate. |journal=J. Histochem. Cytochem. |volume=47 |issue= 9 |pages= 1167-78 |year= 1999 |pmid= 10449538 |doi= }}
*{{cite journal | author=Kuwasako K, Kitamura K, Ito K, ''et al.'' |title=The seven amino acids of human RAMP2 (86) and RAMP3 (59) are critical for agonist binding to human adrenomedullin receptors. |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 49459-65 |year= 2002 |pmid= 11591721 |doi= 10.1074/jbc.M108369200 }}
*{{cite journal | author=Forneris M, Gottardo L, Albertin G, ''et al.'' |title=Expression and function of adrenomedullin and its receptors in Conn's adenoma cells. |journal=Int. J. Mol. Med. |volume=8 |issue= 6 |pages= 675-9 |year= 2002 |pmid= 11712085 |doi= }}
*{{cite journal | author=Hänze J, Groneberg DA, Rose F, ''et al.'' |title=Genomic organization and regulation of a human 7-helix transmembrane receptor which is expressed in pulmonary epithelial cells and induced in hypoxia. |journal=Biochem. Biophys. Res. Commun. |volume=291 |issue= 5 |pages= 1160-5 |year= 2002 |pmid= 11883938 |doi= 10.1006/bbrc.2002.6595 }}
*{{cite journal | author=Dumont CE, Muff R, Flühmann B, ''et al.'' |title=Paracrine/autocrine function of adrenomedullin in peripheral nerves of rats. |journal=Brain Res. |volume=955 |issue= 1-2 |pages= 64-71 |year= 2003 |pmid= 12419522 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Chosa E, Hamada H, Kitamura K, ''et al.'' |title=Expression of adrenomedullin and its receptor by chondrocyte phenotype cells. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 1 |pages= 379-86 |year= 2003 |pmid= 12646214 |doi= }}
*{{cite journal | author=Xu P, Dai AG, Zhou HD, ''et al.'' |title=[Study of the expression and role of adrenomedullin and adrenomedullin receptor in patients with chronic obstructive pulmonary disease] |journal=Zhonghua Jie He He Hu Xi Za Zhi |volume=26 |issue= 12 |pages= 765-8 |year= 2004 |pmid= 14720432 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on EDG7... {November 25, 2007 9:24:30 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:25:31 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
| HGNCid = 14298
| Symbol = EDG7
| AltSymbols =; GPCR; Edg-7; HOFNH30; LP-A3; LPA3; LPAR3; RP4-678I3
| OMIM = 605106
| ECnumber =
| Homologene = 8123
| MGIid = 1929469
| GeneAtlas_image1 = PBB_GE_EDG7_220816_at_tn.png
| Function = {{GNF_GO|id=GO:0001619 |text = lysosphingolipid and lysophosphatidic acid receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008289 |text = lipid binding}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007187 |text = G-protein signaling, coupled to cyclic nucleotide second messenger}} {{GNF_GO|id=GO:0007204 |text = elevation of cytosolic calcium ion concentration}} {{GNF_GO|id=GO:0007268 |text = synaptic transmission}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 23566
| Hs_Ensembl = ENSG00000171517
| Hs_RefseqProtein = NP_036284
| Hs_RefseqmRNA = NM_012152
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 85049873
| Hs_GenLoc_end = 85104430
| Hs_Uniprot = Q9UBY5
| Mm_EntrezGene = 65086
| Mm_Ensembl = ENSMUSG00000036832
| Mm_RefseqmRNA = NM_022983
| Mm_RefseqProtein = NP_075359
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 3
| Mm_GenLoc_start = 146158371
| Mm_GenLoc_end = 146223572
| Mm_Uniprot = Q544B4
}}
}}
'''Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7''', also known as '''EDG7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EDG7 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23566| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.<ref name="entrez">{{cite web | title = Entrez Gene: EDG7 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23566| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Contos JJ, Ishii I, Chun J |title=Lysophosphatidic acid receptors. |journal=Mol. Pharmacol. |volume=58 |issue= 6 |pages= 1188-96 |year= 2001 |pmid= 11093753 |doi= }}
*{{cite journal | author=Bandoh K, Aoki J, Hosono H, ''et al.'' |title=Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. |journal=J. Biol. Chem. |volume=274 |issue= 39 |pages= 27776-85 |year= 1999 |pmid= 10488122 |doi= }}
*{{cite journal | author=Im DS, Heise CE, Harding MA, ''et al.'' |title=Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. |journal=Mol. Pharmacol. |volume=57 |issue= 4 |pages= 753-9 |year= 2000 |pmid= 10727522 |doi= }}
*{{cite journal | author=Fitzgerald LR, Dytko GM, Sarau HM, ''et al.'' |title=Identification of an EDG7 variant, HOFNH30, a G-protein-coupled receptor for lysophosphatidic acid. |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 3 |pages= 805-10 |year= 2000 |pmid= 10891327 |doi= 10.1006/bbrc.2000.2943 }}
*{{cite journal | author=Tokumura A, Sinomiya J, Kishimoto S, ''et al.'' |title=Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids. |journal=Biochem. J. |volume=365 |issue= Pt 3 |pages= 617-28 |year= 2002 |pmid= 11982483 |doi= 10.1042/BJ20020348 }}
*{{cite journal | author=Hama K, Bandoh K, Kakehi Y, ''et al.'' |title=Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors. |journal=FEBS Lett. |volume=523 |issue= 1-3 |pages= 187-92 |year= 2002 |pmid= 12123830 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Cremers B, Flesch M, Kostenis E, ''et al.'' |title=Modulation of myocardial contractility by lysophosphatidic acid (LPA). |journal=J. Mol. Cell. Cardiol. |volume=35 |issue= 1 |pages= 71-80 |year= 2003 |pmid= 12623301 |doi= }}
*{{cite journal | author=Fujita T, Miyamoto S, Onoyama I, ''et al.'' |title=Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer. |journal=Cancer Lett. |volume=192 |issue= 2 |pages= 161-9 |year= 2003 |pmid= 12668280 |doi= }}
*{{cite journal | author=Jin Y, Knudsen E, Wang L, Maghazachi AA |title=Lysophosphatidic acid induces human natural killer cell chemotaxis and intracellular calcium mobilization. |journal=Eur. J. Immunol. |volume=33 |issue= 8 |pages= 2083-9 |year= 2003 |pmid= 12884281 |doi= 10.1002/eji.200323711 }}
*{{cite journal | author=Xing Y, Ganji SH, Noh JW, Kamanna VS |title=Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth. |journal=Am. J. Physiol. Renal Physiol. |volume=287 |issue= 6 |pages= F1250-7 |year= 2005 |pmid= 15292052 |doi= 10.1152/ajprenal.00342.2003 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on GPR124... {November 25, 2007 9:26:59 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:28:02 PM PST}
- CREATED: Created new protein page: GPR124 {November 25, 2007 9:28:10 PM PST}
- INFO: Beginning work on GPR161... {November 25, 2007 9:23:10 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:23:37 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
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| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = G protein-coupled receptor 161
| HGNCid = 23694
| Symbol = GPR161
| AltSymbols =; FLJ33952; RE2
| OMIM =
| ECnumber =
| Homologene = 17824
| MGIid = 2685054
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 23432
| Hs_Ensembl =
| Hs_RefseqProtein = NP_031395
| Hs_RefseqmRNA = NM_007369
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene = 240888
| Mm_Ensembl = ENSMUSG00000040836
| Mm_RefseqmRNA = XM_001002917
| Mm_RefseqProtein = XP_001002917
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 1
| Mm_GenLoc_start = 167142897
| Mm_GenLoc_end = 167147667
| Mm_Uniprot =
}}
}}
'''G protein-coupled receptor 161''', also known as '''GPR161''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR161 G protein-coupled receptor 161| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23432| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Schöneberg T, Schulz A, Gudermann T |title=The structural basis of G-protein-coupled receptor function and dysfunction in human diseases. |journal=Rev. Physiol. Biochem. Pharmacol. |volume=144 |issue= |pages= 143-227 |year= 2002 |pmid= 11987825 |doi= }}
*{{cite journal | author=Raming K, Konzelmann S, Breer H |title=Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone. |journal=Recept. Channels |volume=6 |issue= 2 |pages= 141-51 |year= 1999 |pmid= 9932290 |doi= }}
*{{cite journal | author=Small KM, Seman CA, Castator A, ''et al.'' |title=False positive non-synonymous polymorphisms of G-protein coupled receptor genes. |journal=FEBS Lett. |volume=516 |issue= 1-3 |pages= 253-6 |year= 2002 |pmid= 11959142 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on GPR44... {November 25, 2007 9:17:07 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:18:06 PM PST}
- CREATED: Created new protein page: GPR44 {November 25, 2007 9:18:15 PM PST}
- INFO: Beginning work on HRH3... {November 25, 2007 9:18:15 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:19:28 PM PST}
- CREATED: Created new protein page: HRH3 {November 25, 2007 9:19:36 PM PST}
- INFO: Beginning work on LPHN1... {November 25, 2007 9:20:24 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:21:42 PM PST}
- CREATED: Created new protein page: LPHN1 {November 25, 2007 9:21:51 PM PST}
- INFO: Beginning work on LPHN2... {November 25, 2007 9:21:51 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:22:36 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Latrophilin 2
| HGNCid = 18582
| Symbol = LPHN2
| AltSymbols =; CIRL2; CL2; LEC1; LPHH1
| OMIM = 607018
| ECnumber =
| Homologene = 22712
| MGIid = 2139714
| GeneAtlas_image1 = PBB_GE_LPHN2_206953_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0005529 |text = sugar binding}} {{GNF_GO|id=GO:0016524 |text = latrotoxin receptor activity}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 23266
| Hs_Ensembl = ENSG00000117114
| Hs_RefseqProtein = NP_036434
| Hs_RefseqmRNA = NM_012302
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 81544439
| Hs_GenLoc_end = 82232307
| Hs_Uniprot = O95490
| Mm_EntrezGene = 99633
| Mm_Ensembl = ENSMUSG00000028184
| Mm_RefseqmRNA = XM_888040
| Mm_RefseqProtein = XP_893133
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 3
| Mm_GenLoc_start = 148753242
| Mm_GenLoc_end = 148789342
| Mm_Uniprot = Q0P6A0
}}
}}
'''Latrophilin 2''', also known as '''LPHN2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: LPHN2 latrophilin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23266| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined.<ref name="entrez">{{cite web | title = Entrez Gene: LPHN2 latrophilin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23266| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Südhof TC |title=alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins. |journal=Annu. Rev. Neurosci. |volume=24 |issue= |pages= 933-62 |year= 2001 |pmid= 11520923 |doi= 10.1146/annurev.neuro.24.1.933 }}
*{{cite journal | author=Ushkaryov YA, Volynski KE, Ashton AC |title=The multiple actions of black widow spider toxins and their selective use in neurosecretion studies. |journal=Toxicon |volume=43 |issue= 5 |pages= 527-42 |year= 2004 |pmid= 15066411 |doi= 10.1016/j.toxicon.2004.02.008 }}
*{{cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi= }}
*{{cite journal | author=Nagase T, Ishikawa K, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 5 |pages= 277-86 |year= 1999 |pmid= 9872452 |doi= }}
*{{cite journal | author=White GR, Varley JM, Heighway J |title=Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer. |journal=Oncogene |volume=17 |issue= 26 |pages= 3513-9 |year= 1999 |pmid= 10030676 |doi= 10.1038/sj.onc.1202487 }}
*{{cite journal | author=White GR, Varley JM, Heighway J |title=Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines. |journal=Biochim. Biophys. Acta |volume=1491 |issue= 1-3 |pages= 75-92 |year= 2000 |pmid= 10760572 |doi= }}
*{{cite journal | author=Kreienkamp HJ, Zitzer H, Gundelfinger ED, ''et al.'' |title=The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32387-90 |year= 2000 |pmid= 10964907 |doi= 10.1074/jbc.C000490200 }}
*{{cite journal | author=Bjarnadóttir TK, Fredriksson R, Höglund PJ, ''et al.'' |title=The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. |journal=Genomics |volume=84 |issue= 1 |pages= 23-33 |year= 2005 |pmid= 15203201 |doi= 10.1016/j.ygeno.2003.12.004 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Clark TA, Schweitzer AC, Chen TX, ''et al.'' |title=Discovery of tissue-specific exons using comprehensive human exon microarrays. |journal=Genome Biol. |volume=8 |issue= 4 |pages= R64 |year= 2007 |pmid= 17456239 |doi= 10.1186/gb-2007-8-4-r64 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on LPHN3... {November 25, 2007 9:22:36 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:23:02 PM PST}
- CREATED: Created new protein page: LPHN3 {November 25, 2007 9:23:10 PM PST}
- INFO: Beginning work on NTSR2... {November 25, 2007 9:26:15 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:26:51 PM PST}
- CREATED: Created new protein page: NTSR2 {November 25, 2007 9:26:59 PM PST}
- INFO: Beginning work on OPN3... {November 25, 2007 9:25:31 PM PST}
- CREATE: Found no pages, creating new page. {November 25, 2007 9:26:07 PM PST}
- CREATED: Created new protein page: OPN3 {November 25, 2007 9:26:15 PM PST}
- INFO: Beginning work on OR10J1... {November 25, 2007 9:36:24 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:37:12 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 10, subfamily J, member 1
| HGNCid = 8175
| Symbol = OR10J1
| AltSymbols =; HGMP07J; HSHGMP07J; MGC138495; MGC138497
| OMIM =
| ECnumber =
| Homologene = 8218
| MGIid = 3030052
| GeneAtlas_image1 = PBB_GE_OR10J1_221346_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007338 |text = single fertilization}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26476
| Hs_Ensembl = ENSG00000196184
| Hs_RefseqProtein = NP_036483
| Hs_RefseqmRNA = NM_012351
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 157668618
| Hs_GenLoc_end = 157677135
| Hs_Uniprot = P30954
| Mm_EntrezGene = 258880
| Mm_Ensembl = ENSMUSG00000046643
| Mm_RefseqmRNA = NM_001001809
| Mm_RefseqProtein = NP_001001809
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 1
| Mm_GenLoc_start = 175040033
| Mm_GenLoc_end = 175040974
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 10, subfamily J, member 1''', also known as '''OR10J1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR10J1 olfactory receptor, family 10, subfamily J, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26476| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR10J1 olfactory receptor, family 10, subfamily J, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26476| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR1A2... {November 25, 2007 9:29:11 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:29:50 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 1, subfamily A, member 2
| HGNCid = 8180
| Symbol = OR1A2
| AltSymbols =; MGC119930; MGC119931; OR17-6
| OMIM =
| ECnumber =
| Homologene =
| MGIid =
| GeneAtlas_image1 = PBB_GE_OR1A2_221445_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26189
| Hs_Ensembl = ENSG00000172150
| Hs_RefseqProtein = NP_036484
| Hs_RefseqmRNA = NM_012352
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 17
| Hs_GenLoc_start = 3047561
| Hs_GenLoc_end = 3048492
| Hs_Uniprot = Q9Y585
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 1, subfamily A, member 2''', also known as '''OR1A2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1A2 olfactory receptor, family 1, subfamily A, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26189| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1A2 olfactory receptor, family 1, subfamily A, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26189| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Glusman G, Sosinsky A, Ben-Asher E, ''et al.'' |title=Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. |journal=Genomics |volume=63 |issue= 2 |pages= 227-45 |year= 2000 |pmid= 10673334 |doi= 10.1006/geno.1999.6030 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR1C1... {November 25, 2007 9:28:45 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:29:11 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 1, subfamily C, member 1
| HGNCid = 8182
| Symbol = OR1C1
| AltSymbols =; HSTPCR27; OR1-42; TPCR27
| OMIM =
| ECnumber =
| Homologene = 84795
| MGIid = 3031200
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26188
| Hs_Ensembl = ENSG00000196079
| Hs_RefseqProtein = NP_036485
| Hs_RefseqmRNA = NM_012353
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 245987387
| Hs_GenLoc_end = 245988529
| Hs_Uniprot = Q15619
| Mm_EntrezGene = 258280
| Mm_Ensembl = ENSMUSG00000048996
| Mm_RefseqmRNA = NM_146283
| Mm_RefseqProtein = NP_666395
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 13
| Mm_GenLoc_start = 21544482
| Mm_GenLoc_end = 21545423
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 1, subfamily C, member 1''', also known as '''OR1C1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1C1 olfactory receptor, family 1, subfamily C, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26188| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1C1 olfactory receptor, family 1, subfamily C, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26188| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. |journal=Genomics |volume=39 |issue= 3 |pages= 239-46 |year= 1997 |pmid= 9119360 |doi= 10.1006/geno.1996.4490 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR1F2... {November 25, 2007 9:28:10 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:28:45 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 1, subfamily F, member 2
| HGNCid = 8196
| Symbol = OR1F2
| AltSymbols =; OLFMF2; OR16-3; OR1F11; OR1F2P; OR1F3P; hg91
| OMIM =
| ECnumber =
| Homologene =
| MGIid =
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26184
| Hs_Ensembl =
| Hs_RefseqProtein =
| Hs_RefseqmRNA =
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 1, subfamily F, member 2''', also known as '''OR1F2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1F2 olfactory receptor, family 1, subfamily F, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26184| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1F2 olfactory receptor, family 1, subfamily F, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26184| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Bernot A, Heilig R, Clepet C, ''et al.'' |title=A transcriptional Map of the FMF region. |journal=Genomics |volume=50 |issue= 2 |pages= 147-60 |year= 1998 |pmid= 9653642 |doi= }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR1J4... {November 25, 2007 9:31:33 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:31:54 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 1, subfamily J, member 4
| HGNCid = 8211
| Symbol = OR1J4
| AltSymbols =; HSHTPCRX01; HTPCRX01; OR9-21
| OMIM =
| ECnumber =
| Homologene = 64897
| MGIid = 3030184
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26219
| Hs_Ensembl =
| Hs_RefseqProtein = NP_001004452
| Hs_RefseqmRNA = NM_001004452
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene = 258620
| Mm_Ensembl = ENSMUSG00000050015
| Mm_RefseqmRNA = NM_146627
| Mm_RefseqProtein = NP_666838
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 36672057
| Mm_GenLoc_end = 36672995
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 1, subfamily J, member 4''', also known as '''OR1J4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR1J4 olfactory receptor, family 1, subfamily J, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26219| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR1J4 olfactory receptor, family 1, subfamily J, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26219| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2B6... {November 25, 2007 9:30:23 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:31:33 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily B, member 6
| HGNCid = 8241
| Symbol = OR2B6
| AltSymbols =; MGC120190; MGC129828; OR2B1; OR2B1P; OR2B5; OR2B6P; OR5-40; OR5-41; OR6-31; dJ408B20.2
| OMIM =
| ECnumber =
| Homologene = 40838
| MGIid = 104715
| GeneAtlas_image1 = PBB_GE_OR2B6_216522_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26212
| Hs_Ensembl = ENSG00000124657
| Hs_RefseqProtein = NP_036499
| Hs_RefseqmRNA = NM_012367
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 6
| Hs_GenLoc_start = 28032998
| Hs_GenLoc_end = 28033939
| Hs_Uniprot = P58173
| Mm_EntrezGene = 218066
| Mm_Ensembl = ENSMUSG00000036658
| Mm_RefseqmRNA = NM_146542
| Mm_RefseqProtein = NP_666753
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 13
| Mm_GenLoc_start = 21646045
| Mm_GenLoc_end = 21646986
| Mm_Uniprot = Q2NKW3
}}
}}
'''Olfactory receptor, family 2, subfamily B, member 6''', also known as '''OR2B6''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2B6 olfactory receptor, family 2, subfamily B, member 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26212| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2B6 olfactory receptor, family 2, subfamily B, member 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26212| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Rouquier S, Taviaux S, Trask BJ, ''et al.'' |title=Distribution of olfactory receptor genes in the human genome. |journal=Nat. Genet. |volume=18 |issue= 3 |pages= 243-50 |year= 1998 |pmid= 9500546 |doi= 10.1038/ng0398-243 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2F1... {November 25, 2007 9:29:50 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:30:23 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily F, member 1
| HGNCid = 8246
| Symbol = OR2F1
| AltSymbols =; OLF3; OR14-60; OR2F3; OR2F3P; OR2F4; OR2F5; OR7-139; OR7-140
| OMIM = 608497
| ECnumber =
| Homologene = 69123
| MGIid = 3030287
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26211
| Hs_Ensembl =
| Hs_RefseqProtein = NP_036501
| Hs_RefseqmRNA = NM_012369
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene = 258016
| Mm_Ensembl = ENSMUSG00000048504
| Mm_RefseqmRNA = NM_001011799
| Mm_RefseqProtein = NP_001011799
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 6
| Mm_GenLoc_start = 42673646
| Mm_GenLoc_end = 42674599
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily F, member 1''', also known as '''OR2F1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2F1 olfactory receptor, family 2, subfamily F, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26211| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2F1 olfactory receptor, family 2, subfamily F, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26211| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Issel-Tarver L, Rine J |title=The evolution of mammalian olfactory receptor genes. |journal=Genetics |volume=145 |issue= 1 |pages= 185-95 |year= 1997 |pmid= 9017400 |doi= }}
*{{cite journal | author=Rouquier S, Taviaux S, Trask BJ, ''et al.'' |title=Distribution of olfactory receptor genes in the human genome. |journal=Nat. Genet. |volume=18 |issue= 3 |pages= 243-50 |year= 1998 |pmid= 9500546 |doi= 10.1038/ng0398-243 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Volz A, Ehlers A, Younger R, ''et al.'' |title=Complex transcription and splicing of odorant receptor genes. |journal=J. Biol. Chem. |volume=278 |issue= 22 |pages= 19691-701 |year= 2003 |pmid= 12637542 |doi= 10.1074/jbc.M212424200 }}
*{{cite journal | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2K2... {November 25, 2007 9:33:05 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:34:07 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily K, member 2
| HGNCid = 8264
| Symbol = OR2K2
| AltSymbols =; HSHTPCRH06; HTPCRH06; MGC133152; OR2AN1P; OR2AR1P
| OMIM =
| ECnumber =
| Homologene = 17436
| MGIid = 3030101
| GeneAtlas_image1 = PBB_GE_OR2K2_gnf1h11040_at_tn.png
| GeneAtlas_image2 = PBB_GE_OR2K2_gnf1h11045_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26248
| Hs_Ensembl = ENSG00000171133
| Hs_RefseqProtein = NP_995581
| Hs_RefseqmRNA = NM_205859
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 9
| Hs_GenLoc_start = 113129584
| Hs_GenLoc_end = 113130621
| Hs_Uniprot = Q8NGT1
| Mm_EntrezGene = 258922
| Mm_Ensembl = ENSMUSG00000043385
| Mm_RefseqmRNA = NM_146920
| Mm_RefseqProtein = NP_667131
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 4
| Mm_GenLoc_start = 58878833
| Mm_GenLoc_end = 58879774
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily K, member 2''', also known as '''OR2K2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26248| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26248| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Aloni R, Olender T, Lancet D |title=Ancient genomic architecture for mammalian olfactory receptor clusters. |journal=Genome Biol. |volume=7 |issue= 10 |pages= R88 |year= 2007 |pmid= 17010214 |doi= 10.1186/gb-2006-7-10-r88 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2L2... {November 25, 2007 9:32:38 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:33:05 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily L, member 2
| HGNCid = 8266
| Symbol = OR2L2
| AltSymbols =; HSHTPCRH07; HTPCRH07; OR1-48; OR2L12; OR2L4P
| OMIM =
| ECnumber =
| Homologene = 78689
| MGIid =
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26246
| Hs_Ensembl = ENSG00000203663
| Hs_RefseqProtein = NP_001004686
| Hs_RefseqmRNA = NM_001004686
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 246268193
| Hs_GenLoc_end = 246269131
| Hs_Uniprot = Q8NH16
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily L, member 2''', also known as '''OR2L2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26246| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26246| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2M4... {November 25, 2007 9:31:54 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:32:38 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily M, member 4
| HGNCid = 8270
| Symbol = OR2M4
| AltSymbols =; HSHTPCRX18; HTPCRX18; OR1-55; OST710; TPCR100
| OMIM =
| ECnumber =
| Homologene = 88846
| MGIid =
| GeneAtlas_image1 = PBB_GE_OR2M4_gnf1h05779_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26245
| Hs_Ensembl = ENSG00000171180
| Hs_RefseqProtein = NP_059974
| Hs_RefseqmRNA = NM_017504
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 246468854
| Hs_GenLoc_end = 246469789
| Hs_Uniprot = Q96R27
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily M, member 4''', also known as '''OR2M4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26245| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26245| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M |title=Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. |journal=Genomics |volume=39 |issue= 3 |pages= 239-46 |year= 1997 |pmid= 9119360 |doi= 10.1006/geno.1996.4490 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR52A1... {November 25, 2007 9:23:38 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:24:30 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 52, subfamily A, member 1
| HGNCid = 8318
| Symbol = OR52A1
| AltSymbols =; HPFH1OR
| OMIM =
| ECnumber =
| Homologene = 85928
| MGIid =
| GeneAtlas_image1 = PBB_GE_OR52A1_221329_at_tn.png
| Function = {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 23538
| Hs_Ensembl = ENSG00000182070
| Hs_RefseqProtein = NP_036507
| Hs_RefseqmRNA = NM_012375
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 5128815
| Hs_GenLoc_end = 5164188
| Hs_Uniprot = Q9UKL2
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 52, subfamily A, member 1''', also known as '''OR52A1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23538| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Feingold EA, Penny LA, Nienhuis AW, Forget BG |title=An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells. |journal=Genomics |volume=61 |issue= 1 |pages= 15-23 |year= 1999 |pmid= 10512676 |doi= 10.1006/geno.1999.5935 }}
*{{cite journal | author=Bulger M, Bender MA, van Doorninck JH, ''et al.'' |title=Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14560-5 |year= 2001 |pmid= 11121057 |doi= 10.1073/pnas.97.26.14560 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR5K1... {November 25, 2007 9:35:25 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:36:24 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 5, subfamily K, member 1
| HGNCid = 8349
| Symbol = OR5K1
| AltSymbols =; HSHTPCRX10; HTPCRX10; OR3-8
| OMIM =
| ECnumber =
| Homologene = 45084
| MGIid = 3030007
| GeneAtlas_image1 = PBB_GE_OR5K1_gnf1h10536_at_tn.png
| GeneAtlas_image2 = PBB_GE_OR5K1_gnf1h10538_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26339
| Hs_Ensembl = ENSG00000185408
| Hs_RefseqProtein = NP_001004736
| Hs_RefseqmRNA = NM_001004736
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 3
| Hs_GenLoc_start = 99671111
| Hs_GenLoc_end = 99672062
| Hs_Uniprot = Q8NHB7
| Mm_EntrezGene = 259002
| Mm_Ensembl = ENSMUSG00000049362
| Mm_RefseqmRNA = NM_147000
| Mm_RefseqProtein = NP_667211
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 16
| Mm_GenLoc_start = 58739105
| Mm_GenLoc_end = 58740070
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 5, subfamily K, member 1''', also known as '''OR5K1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26339| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR5K1 olfactory receptor, family 5, subfamily K, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26339| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR5L2... {November 25, 2007 9:34:45 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:35:25 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 5, subfamily L, member 2
| HGNCid = 8351
| Symbol = OR5L2
| AltSymbols =; HSHTPCRX16; HTPCRX16; OR11-153
| OMIM =
| ECnumber =
| Homologene = 72031
| MGIid = 3030990
| GeneAtlas_image1 = PBB_GE_OR5L2_gnf1h05453_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26338
| Hs_Ensembl = ENSG00000205030
| Hs_RefseqProtein = NP_001004739
| Hs_RefseqmRNA = NM_001004739
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 55351271
| Hs_GenLoc_end = 55352206
| Hs_Uniprot = Q8NGL0
| Mm_EntrezGene = 258814
| Mm_Ensembl = ENSMUSG00000075144
| Mm_RefseqmRNA = NM_146817
| Mm_RefseqProtein = NP_667028
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 87750111
| Mm_GenLoc_end = 87751070
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 5, subfamily L, member 2''', also known as '''OR5L2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26338| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR5L2 olfactory receptor, family 5, subfamily L, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26338| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR7A17... {November 25, 2007 9:34:07 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 25, 2007 9:34:45 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 7, subfamily A, member 17
| HGNCid = 8363
| Symbol = OR7A17
| AltSymbols =; BC85395_4; HTPCRX19; MGC126636
| OMIM =
| ECnumber =
| Homologene = 75306
| MGIid = 109316
| GeneAtlas_image1 = PBB_GE_OR7A17_208509_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26333
| Hs_Ensembl = ENSG00000185385
| Hs_RefseqProtein = NP_112163
| Hs_RefseqmRNA = NM_030901
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 19
| Hs_GenLoc_start = 14852238
| Hs_GenLoc_end = 14853167
| Hs_Uniprot = O14581
| Mm_EntrezGene = 18316
| Mm_Ensembl = ENSMUSG00000048101
| Mm_RefseqmRNA = NM_146335
| Mm_RefseqProtein = NP_666447
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 16
| Mm_GenLoc_start = 16586613
| Mm_GenLoc_end = 16587542
| Mm_Uniprot = Q62334
}}
}}
'''Olfactory receptor, family 7, subfamily A, member 17''', also known as '''OR7A17''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR7A17 olfactory receptor, family 7, subfamily A, member 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26333| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR7A17 olfactory receptor, family 7, subfamily A, member 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26333| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Parmentier M, Libert F, Schurmans S, ''et al.'' |title=Expression of members of the putative olfactory receptor gene family in mammalian germ cells. |journal=Nature |volume=355 |issue= 6359 |pages= 453-5 |year= 1992 |pmid= 1370859 |doi= 10.1038/355453a0 }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Grimwood J, Gordon LA, Olsen A, ''et al.'' |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}
{{protein-stub}}
end log.
