User:ProteinBoxBot/PBB Log Wiki 11-24-2007-GPCR-C-2

Log file for Protein Box Bot

Log page index: User:ProteinBoxBot/PBB_Log_Index

Protein Status Quick Log - Date: 22:09, 26 November 2007 (UTC)

Proteins without matches (23)

TAS2R10	TAS2R7	GPR84	TAS2R5	CXCR7
GPRC5D	GPRC5C	GPRC5B	GPR173	LGR4
GPR92	LTB4R2	NMUR2	SUCNR1	CCRL1
P2RY13	RXFP3	OR2S2	CYSLTR2	EDG8
TAS2R14	GPR87	TAS2R13

Proteins with a High Potential Match (1)

GPR85

Redirected Proteins (1)

GPR88

Created (12)

GPR84	CXCR7	GPR173	LGR4	GPR92
LTB4R2	SUCNR1	CCRL1	P2RY13	RXFP3
EDG8	GPR87

Manual Inspection (Page not found) (12)

GPR85	TAS2R10	TAS2R7	TAS2R5	GPRC5D
GPRC5C	GPRC5B	NMUR2	OR2S2	CYSLTR2
TAS2R14	TAS2R13

Updated (1)

GPR88

Protein Status Grid - Date: 22:09, 26 November 2007 (UTC)

HUGO Symbol	Action Summary	Target page(s)	WP Symbol Search
GPR85	Manual Inspection (Page not found)	Other Pages: G protein-coupled receptor 85 (No Data); GPR85 (No Data); SREB (Protein Template); Sreb (No Data); SREB2 (No Data); Sreb2 (No Data);	[1]
TAS2R10	Manual Inspection (Page not found)	Other Pages: Taste receptor (Unknown Data); TAS2R10 (No Data); TRB2 (No Data); Trb2 (No Data); MGC126811 (No Data); Mgc126811 (No Data); MGC126813 (No Data); Mgc126813 (No Data); T2R10 (No Data); T2r10 (No Data);	[2]
TAS2R7	Manual Inspection (Page not found)	Other Pages: Taste receptor (Unknown Data); TAS2R7 (No Data); MGC142121 (No Data); Mgc142121 (No Data); T2R7 (No Data); T2r7 (No Data); TRB4 (No Data); Trb4 (No Data);	[3]
GPR84	Created	Other Pages: G protein-coupled receptor 84 (No Data); GPR84 (No Data); EX33 (No Data); Ex33 (No Data); GPCR4 (No Data); Gpcr4 (No Data);	[4]
TAS2R5	Manual Inspection (Page not found)	Other Pages: Taste receptor (Unknown Data); TAS2R5 (No Data); MGC126635 (No Data); Mgc126635 (No Data); MGC126637 (No Data); Mgc126637 (No Data); T2R5 (No Data); T2r5 (No Data);	[5]
CXCR7	Created	Other Pages: Chemokine receptor 7 (No Data); CXCR7 (No Data); RDC1 (No Data); Rdc1 (No Data); CMKOR1 (No Data); Cmkor1 (No Data); GPR159 (No Data); Gpr159 (No Data);	[6]
GPRC5D	Manual Inspection (Page not found)	Other Pages: G protein-coupled receptor (Unknown Data); GPRC5D (No Data); MGC129713 (No Data); Mgc129713 (No Data); MGC129714 (No Data); Mgc129714 (No Data);	[7]
GPRC5C	Manual Inspection (Page not found)	Other Pages: G protein-coupled receptor (Unknown Data); GPRC5C (No Data); MGC131820 (No Data); Mgc131820 (No Data); RAIG-3 (No Data); Raig-3 (No Data); RAIG3 (No Data); Raig3 (No Data);	[8]
GPRC5B	Manual Inspection (Page not found)	Other Pages: G protein-coupled receptor (Unknown Data); GPRC5B (No Data); RAIG-2 (No Data); Raig-2 (No Data); RAIG2 (No Data); Raig2 (No Data);	[9]
GPR173	Created	Other Pages: G protein-coupled receptor 173 (No Data); GPR173 (No Data); SREB3 (No Data); Sreb3 (No Data);	[10]
LGR4	Created	Other Pages: Leucine-rich repeat-containing G protein-coupled receptor 4 (No Data); LGR4 (No Data); GPR48 (No Data); Gpr48 (No Data);	[11]
GPR92	Created	Other Pages: G protein-coupled receptor 92 (No Data); GPR92 (No Data); GPR93 (No Data); Gpr93 (No Data); KPG 010 (No Data); Kpg 010 (No Data); LPA5 (No Data); Lpa5 (No Data); LPAR5 (No Data); Lpar5 (No Data);	[12]
LTB4R2	Created	Other Pages: Leukotriene B4 receptor 2 (No Data); LTB4R2 (No Data); BLT2 (No Data); Blt2 (No Data); BLTR2 (No Data); Bltr2 (No Data); JULF2 (No Data); Julf2 (No Data); KPG 004 (No Data); Kpg 004 (No Data); NOP9 (No Data); Nop9 (No Data);	[13]
NMUR2	Manual Inspection (Page not found)	Other Pages: Neuromedin U receptor 2 (No Data); NMUR2 (No Data); FM4 (Unknown Data); Fm4 (Redirect -> FM4); NMU2R (No Data); Nmu2r (No Data);	[14]
SUCNR1	Created	Other Pages: Succinate receptor 1 (No Data); SUCNR1 (No Data); GPR91 (No Data); Gpr91 (No Data);	[15]
CCRL1	Created	Other Pages: Chemokine receptor-like 1 (No Data); CCRL1 (No Data); CCBP2 (No Data); Ccbp2 (No Data); CCR10 (Codes Found, but no match[skip]); Ccr10 (No Data); CC-CKR-11 (No Data); Cc-ckr-11 (No Data); CCR11 (No Data); Ccr11 (No Data); CCX-CKR (No Data); Ccx-ckr (No Data); CKR-11 (No Data); Ckr-11 (No Data); PPR1 (No Data); Ppr1 (No Data); VSHK1 (No Data); Vshk1 (No Data);	[16]
P2RY13	Created	Other Pages: Purinergic receptor P2Y (No Data); P2RY13 (No Data); GPCR1 (No Data); Gpcr1 (No Data); FKSG77 (No Data); Fksg77 (No Data); GPR86 (No Data); Gpr86 (No Data); GPR94 (No Data); Gpr94 (No Data); P2Y13 (No Data); P2y13 (No Data); SP174 (No Data); Sp174 (No Data);	[17]
RXFP3	Created	Other Pages: Relaxin/insulin-like family peptide receptor 3 (No Data); RXFP3 (No Data); GPCR135 (No Data); Gpcr135 (No Data); MGC141998 (No Data); Mgc141998 (No Data); MGC142000 (No Data); Mgc142000 (No Data); RLN3R1 (No Data); Rln3r1 (No Data); SALPR (No Data); Salpr (No Data);	[18]
OR2S2	Manual Inspection (Page not found)	Other Pages: Olfactory receptor (Unknown Data); OR2S2 (No Data); OR37A (No Data); Or37a (No Data); OST715 (No Data); Ost715 (No Data);	[19]
CYSLTR2	Manual Inspection (Page not found)	Other Pages: Cysteinyl leukotriene receptor 2 (No Data); CYSLTR2 (No Data); GPCR (Redirect -> G protein-coupled receptor); Gpcr (No Data); CYSLT2 (No Data); Cyslt2 (No Data); CYSLT2R (No Data); Cyslt2r (No Data); HG57 (No Data); Hg57 (No Data); HPN321 (No Data); Hpn321 (No Data); KPG 011 (No Data); Kpg 011 (No Data); PSEC0146 (No Data); Psec0146 (No Data); HGPCR21 (No Data); Hgpcr21 (No Data); G protein-coupled receptor (Unknown Data);	[20]
EDG8	Created	Other Pages: Endothelial differentiation (No Data); EDG8 (No Data); Edg-8 (No Data); S1P5 (No Data); S1p5 (No Data); S1PR5 (No Data); S1pr5 (No Data); SPPR-1 (No Data); Sppr-1 (No Data); SPPR-2 (No Data); Sppr-2 (No Data);	[21]
GPR88	Updated	Other Pages: G protein-coupled receptor 88 (No Data); GPR88 (Good Codes + Entrez Match); STRG (No Data); Strg (No Data);	[22]
TAS2R14	Manual Inspection (Page not found)	Other Pages: Taste receptor (Unknown Data); TAS2R14 (No Data); MGC125491 (No Data); Mgc125491 (No Data); MGC125492 (No Data); Mgc125492 (No Data); T2R14 (No Data); T2r14 (No Data); TRB1 (No Data); Trb1 (No Data);	[23]
GPR87	Created	Other Pages: G protein-coupled receptor 87 (No Data); GPR87 (No Data); FKSG78 (No Data); Fksg78 (No Data); GPR95 (No Data); Gpr95 (No Data); KPG 002 (No Data); Kpg 002 (No Data); MGC131898 (No Data); Mgc131898 (No Data);	[24]
TAS2R13	Manual Inspection (Page not found)	Other Pages: Taste receptor (Unknown Data); TAS2R13 (No Data); T2R13 (No Data); T2r13 (No Data); TRB3 (No Data); Trb3 (No Data);	[25]

Vebose Log - Date: 22:09, 26 November 2007 (UTC)

CCRL1

INFO: Beginning work on CCRL1... {November 26, 2007 1:52:01 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:52:34 PM PST}
CREATED: Created new protein page: CCRL1 {November 26, 2007 1:52:42 PM PST}

CXCR7

INFO: Beginning work on CXCR7... {November 26, 2007 2:05:07 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 2:06:14 PM PST}
CREATED: Created new protein page: CXCR7 {November 26, 2007 2:06:23 PM PST}

CYSLTR2

INFO: Beginning work on CYSLTR2... {November 26, 2007 2:06:23 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:07:31 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Cysteinyl leukotriene receptor 2
 | HGNCid = 18274
 | Symbol = CYSLTR2
 | AltSymbols =; GPCR; CYSLT2; CYSLT2R; HG57; HPN321; KPG_011; PSEC0146; hGPCR21
 | OMIM = 605666
 | ECnumber =  
 | Homologene = 10688
 | MGIid = 1917336
 | GeneAtlas_image1 = PBB_GE_CYSLTR2_220813_at_tn.png
 | Function = {{GNF_GO|id=GO:0001631 |text = cysteinyl leukotriene receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} 
 | Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 57105
    | Hs_Ensembl = ENSG00000152207
    | Hs_RefseqProtein = NP_065110
    | Hs_RefseqmRNA = NM_020377
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 13
    | Hs_GenLoc_start = 48178692
    | Hs_GenLoc_end = 48181499
    | Hs_Uniprot = Q9NS75
    | Mm_EntrezGene = 70086
    | Mm_Ensembl = ENSMUSG00000033470
    | Mm_RefseqmRNA = NM_133720
    | Mm_RefseqProtein = NP_598481
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 71764210
    | Mm_GenLoc_end = 71784186
    | Mm_Uniprot = Q8R528
  }}
}}
'''Cysteinyl leukotriene receptor 2''', also known as '''CYSLTR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CYSLTR2 cysteinyl leukotriene receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57105| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.<ref name="entrez">{{cite web | title = Entrez Gene: CYSLTR2 cysteinyl leukotriene receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57105| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Van Keer C, Kersters K, De Ley J |title=L-Sorbose metabolism in Agrobacterium tumefaciens. |journal=Antonie Van Leeuwenhoek |volume=42 |issue= 1-2 |pages= 13-24 |year= 1976 |pmid= 1085123 |doi=  }}
*{{cite journal  | author=Heise CE, O'Dowd BF, Figueroa DJ, ''et al.'' |title=Characterization of the human cysteinyl leukotriene 2 receptor. |journal=J. Biol. Chem. |volume=275 |issue= 39 |pages= 30531-6 |year= 2000 |pmid= 10851239 |doi= 10.1074/jbc.M003490200 }}
*{{cite journal  | author=Takasaki J, Kamohara M, Matsumoto M, ''et al.'' |title=The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. |journal=Biochem. Biophys. Res. Commun. |volume=274 |issue= 2 |pages= 316-22 |year= 2000 |pmid= 10913337 |doi= 10.1006/bbrc.2000.3140 }}
*{{cite journal  | author=Nothacker HP, Wang Z, Zhu Y, ''et al.'' |title=Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. |journal=Mol. Pharmacol. |volume=58 |issue= 6 |pages= 1601-8 |year= 2001 |pmid= 11093801 |doi=  }}
*{{cite journal  | author=Mita H, Hasegawa M, Saito H, Akiyama K |title=Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. |journal=Clin. Exp. Allergy |volume=31 |issue= 11 |pages= 1714-23 |year= 2002 |pmid= 11696047 |doi=  }}
*{{cite journal  | author=Takeda S, Kadowaki S, Haga T, ''et al.'' |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1-3 |pages= 97-101 |year= 2002 |pmid= 12044878 |doi=  }}
*{{cite journal  | author=Shirasaki H, Kanaizumi E, Watanabe K, ''et al.'' |title=Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa. |journal=Clin. Exp. Allergy |volume=32 |issue= 7 |pages= 1007-12 |year= 2003 |pmid= 12100046 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Sjöström M, Johansson AS, Schröder O, ''et al.'' |title=Dominant expression of the CysLT2 receptor accounts for calcium signaling by cysteinyl leukotrienes in human umbilical vein endothelial cells. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=23 |issue= 8 |pages= e37-41 |year= 2004 |pmid= 12816881 |doi= 10.1161/01.ATV.0000082689.46538.DF }}
*{{cite journal  | author=Mellor EA, Frank N, Soler D, ''et al.'' |title=Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 20 |pages= 11589-93 |year= 2003 |pmid= 13679572 |doi= 10.1073/pnas.2034927100 }}
*{{cite journal  | author=Thompson MD, Storm van's Gravesande K, Galczenski H, ''et al.'' |title=A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha. |journal=Pharmacogenetics |volume=13 |issue= 10 |pages= 641-9 |year= 2004 |pmid= 14515063 |doi= 10.1097/01.fpc.0000054127.14659.42 }}
*{{cite journal  | author=Dunham A, Matthews LH, Burton J, ''et al.'' |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522-8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 }}
*{{cite journal  | author=Fukai H, Ogasawara Y, Migita O, ''et al.'' |title=Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma. |journal=Pharmacogenetics |volume=14 |issue= 10 |pages= 683-90 |year= 2005 |pmid= 15454733 |doi=  }}
*{{cite journal  | author=Pillai SG, Cousens DJ, Barnes AA, ''et al.'' |title=A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma. |journal=Pharmacogenetics |volume=14 |issue= 9 |pages= 627-33 |year= 2005 |pmid= 15475736 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Hui Y, Cheng Y, Smalera I, ''et al.'' |title=Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure. |journal=Circulation |volume=110 |issue= 21 |pages= 3360-6 |year= 2005 |pmid= 15545522 |doi= 10.1161/01.CIR.0000147775.50954.AA }}
*{{cite journal  | author=Corrigan C, Mallett K, Ying S, ''et al.'' |title=Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis. |journal=J. Allergy Clin. Immunol. |volume=115 |issue= 2 |pages= 316-22 |year= 2005 |pmid= 15696087 |doi= 10.1016/j.jaci.2004.10.051 }}
*{{cite journal  | author=Uzonyi B, Lötzer K, Jahn S, ''et al.'' |title=Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 16 |pages= 6326-31 |year= 2006 |pmid= 16606835 |doi= 10.1073/pnas.0601223103 }}
*{{cite journal  | author=Woszczek G, Chen LY, Nagineni S, ''et al.'' |title=IFN-gamma induces cysteinyl leukotriene receptor 2 expression and enhances the responsiveness of human endothelial cells to cysteinyl leukotrienes. |journal=J. Immunol. |volume=178 |issue= 8 |pages= 5262-70 |year= 2007 |pmid= 17404310 |doi=  }}
*{{cite journal  | author=Klotsman M, York TP, Pillai SG, ''et al.'' |title=Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast. |journal=Pharmacogenet. Genomics |volume=17 |issue= 3 |pages= 189-96 |year= 2007 |pmid= 17460547 |doi= 10.1097/FPC.0b013e3280120043 }}
}}
{{refend}}

{{protein-stub}}

EDG8

INFO: Beginning work on EDG8... {November 26, 2007 1:53:56 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:54:52 PM PST}
CREATED: Created new protein page: EDG8 {November 26, 2007 1:55:01 PM PST}

GPR173

INFO: Beginning work on GPR173... {November 26, 2007 1:58:23 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:59:14 PM PST}
CREATED: Created new protein page: GPR173 {November 26, 2007 1:59:22 PM PST}

GPR84

INFO: Beginning work on GPR84... {November 26, 2007 1:56:08 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:56:56 PM PST}
CREATED: Created new protein page: GPR84 {November 26, 2007 1:57:04 PM PST}

GPR85

INFO: Beginning work on GPR85... {November 26, 2007 1:59:22 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:00:03 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = G protein-coupled receptor 85
 | HGNCid = 4536
 | Symbol = GPR85
 | AltSymbols =; SREB; SREB2
 | OMIM = 605188
 | ECnumber =  
 | Homologene = 10355
 | MGIid = 1927851
 | GeneAtlas_image1 = PBB_GE_GPR85_219898_at_tn.png
 | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} 
 | Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 54329
    | Hs_Ensembl = ENSG00000164604
    | Hs_RefseqProtein = NP_061843
    | Hs_RefseqmRNA = NM_018970
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 112507704
    | Hs_GenLoc_end = 112515015
    | Hs_Uniprot = P60893
    | Mm_EntrezGene = 64450
    | Mm_Ensembl = ENSMUSG00000048216
    | Mm_RefseqmRNA = NM_145066
    | Mm_RefseqProtein = NP_659503
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 13785071
    | Mm_GenLoc_end = 13789848
    | Mm_Uniprot = Q6ZWR2
  }}
}}
'''G protein-coupled receptor 85''', also known as '''GPR85''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR85 G protein-coupled receptor 85| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54329| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = 
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097-108 |year= 1999 |pmid= 9847074 |doi=  }}
*{{cite journal  | author=Matsumoto M, Saito T, Takasaki J, ''et al.'' |title=An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system. |journal=Biochem. Biophys. Res. Commun. |volume=272 |issue= 2 |pages= 576-82 |year= 2000 |pmid= 10833454 |doi= 10.1006/bbrc.2000.2829 }}
*{{cite journal  | author=Hellebrand S, Schaller HC, Wittenberger T |title=The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31. |journal=Biochim. Biophys. Acta |volume=1493 |issue= 1-2 |pages= 269-72 |year= 2000 |pmid= 10978537 |doi=  }}
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal  | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
*{{cite journal  | author=Jeon J, Kim C, Sun W, ''et al.'' |title=Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor. |journal=Biochem. Biophys. Res. Commun. |volume=298 |issue= 4 |pages= 613-8 |year= 2002 |pmid= 12408996 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal  | author=Matsumoto M, Beltaifa S, Weickert CS, ''et al.'' |title=A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain. |journal=Brain Res. Mol. Brain Res. |volume=138 |issue= 1 |pages= 58-69 |year= 2005 |pmid= 15893849 |doi= 10.1016/j.molbrainres.2005.04.002 }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
}}
{{refend}}

{{protein-stub}}

GPR87

INFO: Beginning work on GPR87... {November 26, 2007 1:57:04 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:57:45 PM PST}
CREATED: Created new protein page: GPR87 {November 26, 2007 1:57:52 PM PST}

GPR88

INFO: Beginning work on GPR88... {November 26, 2007 1:57:52 PM PST}
SEARCH REDIRECT: Control Box Found: GPR88 {November 26, 2007 1:58:13 PM PST}
UPDATE PROTEIN BOX: Updating Protein Box, No errors. {November 26, 2007 1:58:18 PM PST}
UPDATE SUMMARY: Updating Summary, No Errors. {November 26, 2007 1:58:18 PM PST}
UPDATE CITATIONS: Updating Citations, No Errors. {November 26, 2007 1:58:18 PM PST}
UPDATED: Updated protein page: GPR88 {November 26, 2007 1:58:23 PM PST}

GPR92

INFO: Beginning work on GPR92... {November 26, 2007 2:07:31 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 2:07:59 PM PST}
CREATED: Created new protein page: GPR92 {November 26, 2007 2:08:11 PM PST}

GPRC5B

INFO: Beginning work on GPRC5B... {November 26, 2007 1:52:42 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 1:53:56 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = G protein-coupled receptor, family C, group 5, member B
 | HGNCid = 13308
 | Symbol = GPRC5B
 | AltSymbols =; RAIG-2; RAIG2
 | OMIM = 605948
 | ECnumber =  
 | Homologene = 9435
 | MGIid = 1927596
 | GeneAtlas_image1 = PBB_GE_GPRC5B_203632_s_at_tn.png
 | GeneAtlas_image2 = PBB_GE_GPRC5B_203631_s_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005118 |text = sevenless binding}} {{GNF_GO|id=GO:0008067 |text = metabotropic glutamate, GABA-B-like receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007601 |text = visual perception}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 51704
    | Hs_Ensembl = ENSG00000167191
    | Hs_RefseqProtein = NP_057319
    | Hs_RefseqmRNA = NM_016235
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 19777796
    | Hs_GenLoc_end = 19803652
    | Hs_Uniprot = Q9NZH0
    | Mm_EntrezGene = 64297
    | Mm_Ensembl = ENSMUSG00000008734
    | Mm_RefseqmRNA = NM_022420
    | Mm_RefseqProtein = NP_071865
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 118763196
    | Mm_GenLoc_end = 118786310
    | Mm_Uniprot = Q9JMF0
  }}
}}
'''G protein-coupled receptor, family C, group 5, member B''', also known as '''GPRC5B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5B G protein-coupled receptor, family C, group 5, member B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51704| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade.<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5B G protein-coupled receptor, family C, group 5, member B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51704| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Loftus BJ, Kim UJ, Sneddon VP, ''et al.'' |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295-308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 }}
*{{cite journal  | author=Bräuner-Osborne H, Krogsgaard-Larsen P |title=Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain. |journal=Genomics |volume=65 |issue= 2 |pages= 121-8 |year= 2000 |pmid= 10783259 |doi= 10.1006/geno.2000.6164 }}
*{{cite journal  | author=Robbins MJ, Michalovich D, Hill J, ''et al.'' |title=Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). |journal=Genomics |volume=67 |issue= 1 |pages= 8-18 |year= 2001 |pmid= 10945465 |doi= 10.1006/geno.2000.6226 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
}}
{{refend}}

{{protein-stub}}

GPRC5C

INFO: Beginning work on GPRC5C... {November 26, 2007 2:01:55 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:02:50 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = G protein-coupled receptor, family C, group 5, member C
 | HGNCid = 13309
 | Symbol = GPRC5C
 | AltSymbols =; MGC131820; RAIG-3; RAIG3
 | OMIM = 605949
 | ECnumber =  
 | Homologene = 11099
 | MGIid = 1917605
 | GeneAtlas_image1 = PBB_GE_GPRC5C_219327_s_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008067 |text = metabotropic glutamate, GABA-B-like receptor activity}} 
 | Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55890
    | Hs_Ensembl = ENSG00000170412
    | Hs_RefseqProtein = NP_061123
    | Hs_RefseqmRNA = NM_018653
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 69938647
    | Hs_GenLoc_end = 69958314
    | Hs_Uniprot = Q9NQ84
    | Mm_EntrezGene = 70355
    | Mm_Ensembl = ENSMUSG00000051043
    | Mm_RefseqmRNA = XM_973134
    | Mm_RefseqProtein = XP_978228
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 114667631
    | Mm_GenLoc_end = 114688442
    | Mm_Uniprot = Q8CEU2
  }}
}}
'''G protein-coupled receptor, family C, group 5, member C''', also known as '''GPRC5C''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5C G protein-coupled receptor, family C, group 5, member C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55890| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5C G protein-coupled receptor, family C, group 5, member C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55890| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Bräuner-Osborne H, Krogsgaard-Larsen P |title=Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain. |journal=Genomics |volume=65 |issue= 2 |pages= 121-8 |year= 2000 |pmid= 10783259 |doi= 10.1006/geno.2000.6164 }}
*{{cite journal  | author=Robbins MJ, Michalovich D, Hill J, ''et al.'' |title=Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). |journal=Genomics |volume=67 |issue= 1 |pages= 8-18 |year= 2001 |pmid= 10945465 |doi= 10.1006/geno.2000.6226 }}
*{{cite journal  | author=Bräuner-Osborne H, Jensen AA, Sheppard PO, ''et al.'' |title=Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D. |journal=Biochim. Biophys. Acta |volume=1518 |issue= 3 |pages= 237-48 |year= 2001 |pmid= 11311935 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Lehner B, Semple JI, Brown SE, ''et al.'' |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153-67 |year= 2004 |pmid= 14667819 |doi=  }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
}}
{{refend}}

{{protein-stub}}

GPRC5D

INFO: Beginning work on GPRC5D... {November 26, 2007 2:01:14 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:01:55 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = G protein-coupled receptor, family C, group 5, member D
 | HGNCid = 13310
 | Symbol = GPRC5D
 | AltSymbols =; MGC129713; MGC129714
 | OMIM = 607437
 | ECnumber =  
 | Homologene = 10250
 | MGIid = 1935037
 | GeneAtlas_image1 = PBB_GE_GPRC5D_221297_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005118 |text = sevenless binding}} {{GNF_GO|id=GO:0008067 |text = metabotropic glutamate, GABA-B-like receptor activity}} 
 | Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007601 |text = visual perception}} {{GNF_GO|id=GO:0031424 |text = keratinization}} {{GNF_GO|id=GO:0042633 |text = hair cycle}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55507
    | Hs_Ensembl = ENSG00000111291
    | Hs_RefseqProtein = NP_061124
    | Hs_RefseqmRNA = NM_018654
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 12984976
    | Hs_GenLoc_end = 12994585
    | Hs_Uniprot = Q9NZD1
    | Mm_EntrezGene = 93746
    | Mm_Ensembl = ENSMUSG00000030205
    | Mm_RefseqmRNA = NM_053118
    | Mm_RefseqProtein = NP_444348
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 135071684
    | Mm_GenLoc_end = 135082600
    | Mm_Uniprot = Q0VEL2
  }}
}}
'''G protein-coupled receptor, family C, group 5, member D''', also known as '''GPRC5D''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5D G protein-coupled receptor, family C, group 5, member D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55507| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not yet been determined.<ref name="entrez">{{cite web | title = Entrez Gene: GPRC5D G protein-coupled receptor, family C, group 5, member D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55507| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Bräuner-Osborne H, Jensen AA, Sheppard PO, ''et al.'' |title=Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D. |journal=Biochim. Biophys. Acta |volume=1518 |issue= 3 |pages= 237-48 |year= 2001 |pmid= 11311935 |doi=  }}
*{{cite journal  | author=Takeda S, Kadowaki S, Haga T, ''et al.'' |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1-3 |pages= 97-101 |year= 2002 |pmid= 12044878 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}

{{protein-stub}}

LGR4

INFO: Beginning work on LGR4... {November 26, 2007 2:00:29 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 2:01:07 PM PST}
CREATED: Created new protein page: LGR4 {November 26, 2007 2:01:14 PM PST}

LTB4R2

INFO: Beginning work on LTB4R2... {November 26, 2007 2:02:50 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 2:03:22 PM PST}
CREATED: Created new protein page: LTB4R2 {November 26, 2007 2:03:31 PM PST}

NMUR2

INFO: Beginning work on NMUR2... {November 26, 2007 2:04:36 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:05:07 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Neuromedin U receptor 2
 | HGNCid = 16454
 | Symbol = NMUR2
 | AltSymbols =; FM4; NMU2R
 | OMIM = 605108
 | ECnumber =  
 | Homologene = 49618
 | MGIid = 2441765
 | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0001607 |text = neuromedin U receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005229 |text = intracellular calcium activated chloride channel activity}} {{GNF_GO|id=GO:0005525 |text = GTP binding}} 
 | Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} 
 | Process = {{GNF_GO|id=GO:0006816 |text = calcium ion transport}} {{GNF_GO|id=GO:0006940 |text = regulation of smooth muscle contraction}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007200 |text = G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)}} {{GNF_GO|id=GO:0007204 |text = elevation of cytosolic calcium ion concentration}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0007417 |text = central nervous system development}} {{GNF_GO|id=GO:0007631 |text = feeding behavior}} {{GNF_GO|id=GO:0019226 |text = transmission of nerve impulse}} {{GNF_GO|id=GO:0043006 |text = calcium-dependent phospholipase A2 activation}} {{GNF_GO|id=GO:0045045 |text = secretory pathway}} {{GNF_GO|id=GO:0048016 |text = inositol phosphate-mediated signaling}} {{GNF_GO|id=GO:0050482 |text = arachidonic acid secretion}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 56923
    | Hs_Ensembl = ENSG00000132911
    | Hs_RefseqProtein = NP_064552
    | Hs_RefseqmRNA = NM_020167
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 151751303
    | Hs_GenLoc_end = 151765017
    | Hs_Uniprot = Q9GZQ4
    | Mm_EntrezGene = 216749
    | Mm_Ensembl = ENSMUSG00000037393
    | Mm_RefseqmRNA = NM_153079
    | Mm_RefseqProtein = NP_694719
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 55868413
    | Mm_GenLoc_end = 55884410
    | Mm_Uniprot = Q8BZ39
  }}
}}
'''Neuromedin U receptor 2''', also known as '''NMUR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NMUR2 neuromedin U receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56923| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = 
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Tate CG, Grisshammer R |title=Heterologous expression of G-protein-coupled receptors. |journal=Trends Biotechnol. |volume=14 |issue= 11 |pages= 426-30 |year= 1997 |pmid= 8940772 |doi= 10.1016/0167-7799(96)10059-7 }}
*{{cite journal  | author=Hosoya M, Moriya T, Kawamata Y, ''et al.'' |title=Identification and functional characterization of a novel subtype of neuromedin U receptor. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29528-32 |year= 2000 |pmid= 10887190 |doi= 10.1074/jbc.M004261200 }}
*{{cite journal  | author=Howard AD, Wang R, Pong SS, ''et al.'' |title=Identification of receptors for neuromedin U and its role in feeding. |journal=Nature |volume=406 |issue= 6791 |pages= 70-4 |year= 2000 |pmid= 10894543 |doi= 10.1038/35017610 }}
*{{cite journal  | author=Raddatz R, Wilson AE, Artymyshyn R, ''et al.'' |title=Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32452-9 |year= 2000 |pmid= 10899166 |doi= 10.1074/jbc.M004613200 }}
*{{cite journal  | author=Shan L, Qiao X, Crona JH, ''et al.'' |title=Identification of a novel neuromedin U receptor subtype expressed in the central nervous system. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39482-6 |year= 2001 |pmid= 11010960 |doi= 10.1074/jbc.C000522200 }}
*{{cite journal  | author=Fernández Alvarez C, Debeljuk L, Díaz Rodríguez E, Díaz López B |title=Developmental pattern of tachykinins during aging in several organs: effect of exogenous melatonin. |journal=Peptides |volume=23 |issue= 9 |pages= 1617-23 |year= 2003 |pmid= 12217422 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Bhattacharyya S, Luan J, Farooqi IS, ''et al.'' |title=Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor. |journal=J. Endocrinol. |volume=183 |issue= 1 |pages= 115-20 |year= 2004 |pmid= 15525579 |doi= 10.1677/joe.1.05830 }}
*{{cite journal  | author=Mori K, Miyazato M, Ida T, ''et al.'' |title=Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. |journal=EMBO J. |volume=24 |issue= 2 |pages= 325-35 |year= 2005 |pmid= 15635449 |doi= 10.1038/sj.emboj.7600526 }}
*{{cite journal  | author=Fang L, Zhang M, Li C, ''et al.'' |title=Chemical genetic analysis reveals the effects of NMU2R on the expression of peptide hormones. |journal=Neurosci. Lett. |volume=404 |issue= 1-2 |pages= 148-53 |year= 2006 |pmid= 16781063 |doi= 10.1016/j.neulet.2006.05.034 }}
}}
{{refend}}

{{protein-stub}}

OR2S2

INFO: Beginning work on OR2S2... {November 26, 2007 2:03:31 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:04:07 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Olfactory receptor, family 2, subfamily S, member 2
 | HGNCid = 8276
 | Symbol = OR2S2
 | AltSymbols =; OR37A; OST715
 | OMIM =  
 | ECnumber =  
 | Homologene = 84331
 | MGIid =  
 | GeneAtlas_image1 = PBB_GE_OR2S2_221409_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 56656
    | Hs_Ensembl = ENSG00000122718
    | Hs_RefseqProtein = NP_063950
    | Hs_RefseqmRNA = NM_019897
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 35947136
    | Hs_GenLoc_end = 35948095
    | Hs_Uniprot = Q9NQN1
    | Mm_EntrezGene =  
    | Mm_Ensembl =  
    | Mm_RefseqmRNA =  
    | Mm_RefseqProtein =  
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr =  
    | Mm_GenLoc_start =  
    | Mm_GenLoc_end =  
    | Mm_Uniprot =  
  }}
}}
'''Olfactory receptor, family 2, subfamily S, member 2''', also known as '''OR2S2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2S2 olfactory receptor, family 2, subfamily S, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56656| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2S2 olfactory receptor, family 2, subfamily S, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56656| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Strotmann J, Hoppe R, Conzelmann S, ''et al.'' |title=Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization. |journal=Gene |volume=236 |issue= 2 |pages= 281-91 |year= 1999 |pmid= 10452948 |doi=  }}
*{{cite journal  | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Hoppe R, Breer H, Strotmann J |title=Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. |journal=Genomics |volume=82 |issue= 3 |pages= 355-64 |year= 2004 |pmid= 12906860 |doi=  }}
*{{cite journal  | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi=  }}
*{{cite journal  | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
{{refend}}

{{protein-stub}}

P2RY13

INFO: Beginning work on P2RY13... {November 26, 2007 1:55:01 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:55:56 PM PST}
CREATED: Created new protein page: P2RY13 {November 26, 2007 1:56:08 PM PST}

RXFP3

INFO: Beginning work on RXFP3... {November 26, 2007 1:51:09 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 1:51:53 PM PST}
CREATED: Created new protein page: RXFP3 {November 26, 2007 1:52:01 PM PST}

SUCNR1

INFO: Beginning work on SUCNR1... {November 26, 2007 2:04:07 PM PST}
CREATE: Found no pages, creating new page. {November 26, 2007 2:04:29 PM PST}
CREATED: Created new protein page: SUCNR1 {November 26, 2007 2:04:36 PM PST}

TAS2R10

INFO: Beginning work on TAS2R10... {November 26, 2007 1:49:37 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 1:50:22 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Taste receptor, type 2, member 10
 | HGNCid = 14918
 | Symbol = TAS2R10
 | AltSymbols =; TRB2; MGC126811; MGC126813; T2R10
 | OMIM = 604791
 | ECnumber =  
 | Homologene = 41540
 | MGIid = 2681207
 | GeneAtlas_image1 = PBB_GE_TAS2R10_221397_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050909 |text = sensory perception of taste}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 50839
    | Hs_Ensembl = ENSG00000121318
    | Hs_RefseqProtein = NP_076410
    | Hs_RefseqmRNA = NM_023921
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 10869212
    | Hs_GenLoc_end = 10870135
    | Hs_Uniprot = Q9NYW0
    | Mm_EntrezGene = 387342
    | Mm_Ensembl = ENSMUSG00000053389
    | Mm_RefseqmRNA = NM_199154
    | Mm_RefseqProtein = NP_954605
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 131624851
    | Mm_GenLoc_end = 131625777
    | Mm_Uniprot = Q7M725
  }}
}}
'''Taste receptor, type 2, member 10''', also known as '''TAS2R10''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R10 taste receptor, type 2, member 10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50839| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R10 taste receptor, type 2, member 10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50839| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507-10 |year= 2000 |pmid= 10774719 |doi=  }}
*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1-4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366-71 |year= 2002 |pmid= 12139982 |doi=  }}
*{{cite journal  | author=Adler E, Hoon MA, Mueller KL, ''et al.'' |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693-702 |year= 2000 |pmid= 10761934 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Mueller KL, Hoon MA, ''et al.'' |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703-11 |year= 2000 |pmid= 10761935 |doi=  }}
*{{cite journal  | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601-4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293-301 |year= 2003 |pmid= 12581520 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432-6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313-26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
*{{cite journal  | author=Mueller KL, Hoon MA, Erlenbach I, ''et al.'' |title=The receptors and coding logic for bitter taste. |journal=Nature |volume=434 |issue= 7030 |pages= 225-9 |year= 2005 |pmid= 15759003 |doi= 10.1038/nature03352 }}
}}
{{refend}}

{{protein-stub}}

TAS2R13

INFO: Beginning work on TAS2R13... {November 26, 2007 1:49:15 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 1:49:37 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Taste receptor, type 2, member 13
 | HGNCid = 14919
 | Symbol = TAS2R13
 | AltSymbols =; T2R13; TRB3
 | OMIM = 604792
 | ECnumber =  
 | Homologene = 41542
 | MGIid = 2681259
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050909 |text = sensory perception of taste}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 50838
    | Hs_Ensembl =  
    | Hs_RefseqProtein = NP_076409
    | Hs_RefseqmRNA = NM_023920
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr =  
    | Hs_GenLoc_start =  
    | Hs_GenLoc_end =  
    | Hs_Uniprot =  
    | Mm_EntrezGene = 387349
    | Mm_Ensembl = ENSMUSG00000071150
    | Mm_RefseqmRNA = NM_207024
    | Mm_RefseqProtein = NP_996907
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 132665783
    | Mm_GenLoc_end = 132666700
    | Mm_Uniprot = Q7M720
  }}
}}
'''Taste receptor, type 2, member 13''', also known as '''TAS2R13''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R13 taste receptor, type 2, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50838| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R13 taste receptor, type 2, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50838| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507-10 |year= 2000 |pmid= 10774719 |doi=  }}
*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1-4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366-71 |year= 2002 |pmid= 12139982 |doi=  }}
*{{cite journal  | author=Adler E, Hoon MA, Mueller KL, ''et al.'' |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693-702 |year= 2000 |pmid= 10761934 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Mueller KL, Hoon MA, ''et al.'' |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703-11 |year= 2000 |pmid= 10761935 |doi=  }}
*{{cite journal  | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601-4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293-301 |year= 2003 |pmid= 12581520 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432-6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313-26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
}}
{{refend}}

{{protein-stub}}

TAS2R14

INFO: Beginning work on TAS2R14... {November 26, 2007 1:50:22 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 1:51:09 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Taste receptor, type 2, member 14
 | HGNCid = 14920
 | Symbol = TAS2R14
 | AltSymbols =; MGC125491; MGC125492; T2R14; TRB1
 | OMIM = 604790
 | ECnumber =  
 | Homologene = 87013
 | MGIid = 2681298
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050909 |text = sensory perception of taste}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 50840
    | Hs_Ensembl =  
    | Hs_RefseqProtein = NP_076411
    | Hs_RefseqmRNA = NM_023922
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr =  
    | Hs_GenLoc_start =  
    | Hs_GenLoc_end =  
    | Hs_Uniprot =  
    | Mm_EntrezGene = 387616
    | Mm_Ensembl = ENSMUSG00000071147
    | Mm_RefseqmRNA = NM_021562
    | Mm_RefseqProtein = NP_067537
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 133020548
    | Mm_GenLoc_end = 133021486
    | Mm_Uniprot = Q7TQA4
  }}
}}
'''Taste receptor, type 2, member 14''', also known as '''TAS2R14''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R14 taste receptor, type 2, member 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50840| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R14 taste receptor, type 2, member 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50840| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507-10 |year= 2000 |pmid= 10774719 |doi=  }}
*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1-4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366-71 |year= 2002 |pmid= 12139982 |doi=  }}
*{{cite journal  | author=Adler E, Hoon MA, Mueller KL, ''et al.'' |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693-702 |year= 2000 |pmid= 10761934 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Mueller KL, Hoon MA, ''et al.'' |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703-11 |year= 2000 |pmid= 10761935 |doi=  }}
*{{cite journal  | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601-4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293-301 |year= 2003 |pmid= 12581520 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432-6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313-26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
*{{cite journal  | author=Liu T, Qian WJ, Gritsenko MA, ''et al.'' |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070-80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065 }}
*{{cite journal  | author=Behrens M, Bartelt J, Reichling C, ''et al.'' |title=Members of RTP and REEP gene families influence functional bitter taste receptor expression. |journal=J. Biol. Chem. |volume=281 |issue= 29 |pages= 20650-9 |year= 2006 |pmid= 16720576 |doi= 10.1074/jbc.M513637200 }}
}}
{{refend}}

{{protein-stub}}

TAS2R5

INFO: Beginning work on TAS2R5... {November 26, 2007 2:00:03 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:00:29 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Taste receptor, type 2, member 5
 | HGNCid = 14912
 | Symbol = TAS2R5
 | AltSymbols =; MGC126635; MGC126637; T2R5
 | OMIM = 605062
 | ECnumber =  
 | Homologene = 49580
 | MGIid =  
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007635 |text = chemosensory behavior}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050909 |text = sensory perception of taste}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 54429
    | Hs_Ensembl = ENSG00000127366
    | Hs_RefseqProtein = NP_061853
    | Hs_RefseqmRNA = NM_018980
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 141136486
    | Hs_GenLoc_end = 141137635
    | Hs_Uniprot = Q9NYW4
    | Mm_EntrezGene =  
    | Mm_Ensembl =  
    | Mm_RefseqmRNA =  
    | Mm_RefseqProtein =  
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr =  
    | Mm_GenLoc_start =  
    | Mm_GenLoc_end =  
    | Mm_Uniprot =  
  }}
}}
'''Taste receptor, type 2, member 5''', also known as '''TAS2R5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R5 taste receptor, type 2, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54429| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception.<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R5 taste receptor, type 2, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54429| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507-10 |year= 2000 |pmid= 10774719 |doi=  }}
*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1-4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366-71 |year= 2002 |pmid= 12139982 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS |title=The receptors and cells for mammalian taste. |journal=Nature |volume=444 |issue= 7117 |pages= 288-94 |year= 2007 |pmid= 17108952 |doi= 10.1038/nature05401 }}
*{{cite journal  | author=Dias Neto E, Correa RG, Verjovski-Almeida S, ''et al.'' |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491-6 |year= 2000 |pmid= 10737800 |doi=  }}
*{{cite journal  | author=Adler E, Hoon MA, Mueller KL, ''et al.'' |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693-702 |year= 2000 |pmid= 10761934 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Mueller KL, Hoon MA, ''et al.'' |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703-11 |year= 2000 |pmid= 10761935 |doi=  }}
*{{cite journal  | author=Firestein S |title=The good taste of genomics. |journal=Nature |volume=404 |issue= 6778 |pages= 552-3 |year= 2000 |pmid= 10766221 |doi= 10.1038/35007167 }}
*{{cite journal  | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601-4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293-301 |year= 2003 |pmid= 12581520 |doi=  }}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432-6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313-26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
}}
{{refend}}

{{protein-stub}}

TAS2R7

INFO: Beginning work on TAS2R7... {November 26, 2007 1:48:31 PM PST}
AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 1:49:15 PM PST}

 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes 
| require_manual_inspection = no 
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}

<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
 | image =  
 | image_source =  
 | PDB = 
 | Name = Taste receptor, type 2, member 7
 | HGNCid = 14913
 | Symbol = TAS2R7
 | AltSymbols =; MGC142121; T2R7; TRB4
 | OMIM = 604793
 | ECnumber =  
 | Homologene = 41536
 | MGIid = 2681278
 | GeneAtlas_image1 = PBB_GE_TAS2R7_221396_at_tn.png
 | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} 
 | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} 
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050909 |text = sensory perception of taste}} 
 | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 50837
    | Hs_Ensembl = ENSG00000121377
    | Hs_RefseqProtein = NP_076408
    | Hs_RefseqmRNA = NM_023919
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 10845480
    | Hs_GenLoc_end = 10846436
    | Hs_Uniprot = Q9NYW3
    | Mm_EntrezGene = 387355
    | Mm_Ensembl = ENSMUSG00000054497
    | Mm_RefseqmRNA = NM_199156
    | Mm_RefseqProtein = NP_954607
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 131595585
    | Mm_GenLoc_end = 131596523
    | Mm_Uniprot = Q0VE81
  }}
}}
'''Taste receptor, type 2, member 7''', also known as '''TAS2R7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R7 taste receptor, type 2, member 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50837| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title = 
| summary_text = This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.<ref name="entrez">{{cite web | title = Entrez Gene: TAS2R7 taste receptor, type 2, member 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50837| accessdate = }}</ref>
}}

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading 
| citations = 
*{{cite journal  | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507-10 |year= 2000 |pmid= 10774719 |doi=  }}
*{{cite journal  | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1-4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal  | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366-71 |year= 2002 |pmid= 12139982 |doi=  }}
*{{cite journal  | author=Adler E, Hoon MA, Mueller KL, ''et al.'' |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693-702 |year= 2000 |pmid= 10761934 |doi=  }}
*{{cite journal  | author=Chandrashekar J, Mueller KL, Hoon MA, ''et al.'' |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703-11 |year= 2000 |pmid= 10761935 |doi=  }}
*{{cite journal  | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601-4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang Y, Hoon MA, Chandrashekar J, ''et al.'' |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293-301 |year= 2003 |pmid= 12581520 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432-6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal  | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313-26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 }}
}}
{{refend}}

{{protein-stub}}

end log.