Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene.[5][6] It is one of seven proteins in the COPI coatomer complex that coats vesicles as they bud from the Golgi complex.[5]

COPG1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCOPG1, COPG, coatomer protein complex subunit gamma 1, COPI coat complex subunit gamma 1
External IDsOMIM: 615525; MGI: 1858696; HomoloGene: 56745; GeneCards: COPG1; OMA:COPG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016128

NM_017477
NM_201244

RefSeq (protein)

NP_057212

NP_059505
NP_957696

Location (UCSC)Chr 3: 129.25 – 129.28 MbChr 6: 87.86 – 87.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

edit

COPG has been shown to interact with Dopamine receptor D1,[7] COPZ1[5][8] and COPB1.[5][9]

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181789Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030058Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b c d Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (February 2001). "Identification and characterization of novel isoforms of COP I subunits". J Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
  6. ^ "Entrez Gene: COPG coatomer protein complex, subunit gamma".
  7. ^ Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou Qun-Yong (February 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2). Germany: 77–85. doi:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085.
  8. ^ Faulstich, D; Auerbach S; Orci L; Ravazzola M; Wegchingel S; Lottspeich F; Stenbeck G; Harter C; Wieland F T; Tschochner H (October 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1). UNITED STATES: 53–61. doi:10.1083/jcb.135.1.53. ISSN 0021-9525. PMC 2121028. PMID 8858162.
  9. ^ Lowe, M; Kreis T E (November 1996). "In vivo assembly of coatomer, the COP-I coat precursor". J. Biol. Chem. 271 (48). UNITED STATES: 30725–30. doi:10.1074/jbc.271.48.30725. ISSN 0021-9258. PMID 8940050.
edit

Further reading

edit