ADGRF2P

ADGRF2P
Identifiers
Aliases	ADGRF2P, PGR20, hGPCR35, GPR111, adhesion G protein-coupled receptor F2, ADGRF2, adhesion G protein-coupled receptor F2, pseudogene
External IDs	MGI: 2182728; GeneCards: ADGRF2P
Gene location (Human)
Chr.	Chromosome 6 (human)
End	47,695,192 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	43,053,070 bp
RNA expression pattern
	Top expressed in
	testicle; ; right uterine tube; ; skin of leg; ; skin of abdomen; ; apex of heart; ; olfactory zone of nasal mucosa; ; left ventricle; ; ganglionic eminence; ; right auricle of heart; ; muscle of leg;
	Top expressed in
	esophagus; ; lip; ; zone of skin; ; embryo; ; muscle of thigh; ; cerebellar cortex; ; quadriceps femoris muscle; ; neural layer of retina; ; olfactory bulb; ; muscle tissue;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	222611
	435529
	ENSG00000164393
	ENSMUSG00000057899
	Q8IZF7
	E9Q4J9
	NM_153839; NM_001368115; NM_001394650
	NM_001033493
	NP_722581; NP_001355044
	NP_001028665
	Wikidata
View/Edit Human	View/Edit Mouse

Adhesion G protein-coupled receptor F2, pseudogene (ADGRF2P) is a putative pseudogene found in humans, and previously called ADGRF2 or GPR111.^[5]^[6]^[7]^[8] Protein-coding orthologs exist in other species.^[8]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164393 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000057899 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yona S, Stacey M, eds. (2010). Adhesion-GPCRs : structure to function. New York: Springer Science+Business Media. ISBN 978-1-4419-7912-4.
↑ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (November 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Letters. 531 (3): 407–414. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.
↑ "Entrez Gene: GPR111 G protein-coupled receptor 111".
1 2 "Q8IZF7 · AGRF2_HUMAN". uniprot.org. UniProt consortium. Retrieved 2026-08-23.

Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (June 2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Letters. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
Fredriksson R, Gloriam DE, Höglund PJ, Lagerström MC, Schiöth HB (February 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochemical and Biophysical Research Communications. 301 (3): 725–734. doi:10.1016/S0006-291X(03)00026-3. PMID 12565841.
Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, et al. (April 2003). "The G protein-coupled receptor repertoires of human and mouse". Proceedings of the National Academy of Sciences of the United States of America. 100 (8): 4903–4908. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Bjarnadóttir TK, Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB (July 2004). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000164393 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000057899 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Yona S, Stacey M, eds. (2010). Adhesion-GPCRs : structure to function. New York: Springer Science+Business Media. ISBN 978-1-4419-7912-4.

[Fredriksson_2002-6] Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (November 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Letters. 531 (3): 407–414. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.

[entrez-7] "Entrez Gene: GPR111 G protein-coupled receptor 111".

[uniprot-8] 1 2 "Q8IZF7 · AGRF2_HUMAN". uniprot.org. UniProt consortium. Retrieved 2026-08-23.

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References

Further reading