| mir-194 microRNA precursor family | |
|---|---|
 Predicted secondary structure and sequence conservation of mir-194 | |
| Identifiers | |
| Symbol | mir-194 |
| Rfam | RF00257 |
| miRBase | MI0000488 |
| miRBase family | MIPF0000055 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | GO:0035195 GO:0035068 |
| SO | SO:0001244 |
| PDB structures | PDBe |
In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin.
References
edit- ^ Lagos-Quintana, Mariana; Rauhut, Reinhard; Meyer, Jutta; Borkhardt, Arndt; Tuschl, Thomas (2003). "New microRNAs from mouse and human". RNA. 9 (2): 175–179. doi:10.1261/rna.2146903. PMC 1370382. PMID 12554859.
{{cite journal}}: CS1 maint: date and year (link) - ^ Michael, M. Z.; O' Connor, S. M.; Van Holst Pellekaan, N. G.; Young, G. P.; James, R. J. (2003). "Reduced accumulation of specific microRNAs in colorectal neoplasia". Mol Cancer Res. 1 (12): 882–891. PMID 14573789.
{{cite journal}}: CS1 maint: date and year (link)
External links
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